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2- isopropyl-2 -chloroethyl

Of this product, 4.5 g in 30 cc of dry isopropyl alcohol are refluxed for 16 hours with 2.5 g of (3-chloroethyl dimethyl amine. The solution is cooled and filtered clear from the solid by-product. The solvent is removed under reduced pressure on the steam bath and the residue is washed with anhydrous ether. It is dissolved in ethyl acetate from which it crystallizes. It is the hydrochloride of (3-(dimethylamino)ethyl ester of 2-phenyl-2-( 1-hy-droxycyclopentyl) ethanoic acid, melting at 134° to 136°C. [Pg.413]

Preparation of 4-( -Chloroethyl)-3,3-Diphenyl-1Ethyl-2-Pyrrolidinone A solution of a,a -diphenyl-a -(1-ethyl-3-pyrrolidyl)-acetonitrile in 70% sulfuric acid was heated at 130°-140°C for 48 hours, poured onto ice, made basic with sodium hydroxide, and extracted with chloroform. The chloroform solution was acidified with hydrogen chloride gas, dried over sodium sulfate and concentrated. The residue was refluxed in 500 ml of thionyl chloride for 3 hours the resulting solution was concentrated in vacuo and the residue was crystallized from isopropyl ether. [Pg.537]

The residue is the 3-N-bis((3-chloroethyl)carbamate of estradiol. The compound melts at 101° to 103°C after recrystallization from isopropyl ether plus hexane (1 1). [Pg.579]

This residue is dissolved in isopropyl alcohol and 1 gram N-bis-chloroethyl-aniline is added to it. The mixture is refluxed for 3 hours. The solvent is removed at a reduced pressure, the residue is treated with 50% potassium carbonate, and extracted with ether. By treating with ethereal hydrochloric acid, 2-N -m-chlorophenylpiperazino-propyl-s-triazole-[4,3-al-pyridine-3-one hydrochloride is precipitated MP 223°C. [Pg.1519]

Methyl m-tolyl (8), ethyl m-tolyl, methyl n-butyl and methyl n-propyl sulfoxides were obtained in 100% e.e. This method was less successful when applied to methyl phenyl sulfoxide (5% e.e.) or to methyl isobutyl and methyl ethyl sulfoxides (25% e.e.). No complexes were formed between methyl o-tolyl, methyl p-tolyl, methyl 2-butyl and methyl isopropyl sulfoxides so these compounds could not be resolved using 7. A crystal structure of the 1 1 complex formed between 7 and 8 revealed that the partners were linked by OH—OS hydrogen bonds in endless zig-zag chains23. More recently, 2-chloroethyl m-tolyl sulfoxide (9) has been resolved using 724. [Pg.58]

N-(2- [Ethoxy(methyl)phosphoryl]sulfanyl ethyl)-IV-isopropyl-N-methylpropan-2-aminium Iodide N-(2- [Ethoxy(methyl)phosphoryl]sulfanyl ethyl)-IV-isopropylpropan-2-aminium Chloride N-(2-Chloroethyl)dimethylamine N-(2-Chloroethyl)-N,N-dimethylamine N-(2-Hydroxyethyl)diethylamine N-(4-Oxy-3-methoxybenzyl)-8-methyl-6-nonenamide N-(Diethylamino)ethanol N-(Isopropyl)-2-propamine... [Pg.678]

N,N-Diethyl-2- [methyl(cyclohexyloxy)phosphoryl]sulfanyl -N-methylethanaminium Iodide N,N-Diethyl-2-aminoethanol N,N-Diethyl-2-hydroxyethylamine N,N-Diethylethanolamine N,N-Diethyl-N-(/3-hydroxyethyl)amine N,N-Diisopropyl-(jS)-aminoethanol N,N-Diisopropyl-2-aminoethanol /V,/V-I)i isopropylamine N,N-Diisopropylaminoethanol /V,/V,-l)iisopropylcarbodiimide N,N-Diisopropylethanolamine N,N-Dimethyl-2-chloroethylamine N/N -DimethyM -bipyridinium /V,/V,-I)imethylhydrazine N,N-Dimethyl-N-(2-chloroethyl)amine /V,/Vd)irnethyl-/i-chloroethylamine /V,/V,-Methanetetrayl Biscyclohexanamine /V./V -Thiod i-2,1 -ethanediyl Bis(N-isopropyl)-2-propanamine N,a-Dimethylphenethylam ine... [Pg.679]

Isopropyl 2-chloroethyl ether, b.p. 118-121°, is formed in variable amounts as a by-product. [Pg.45]

EINECS 203-468-6, see Ethylenediamine EINECS 203-470-7, see Allyl alcohol EINECS 203-472-8, see Chloroacetaldehyde EINECS 203-481-7, see Methyl formate EINECS 203-523-4, see 2-Methylpentane EINECS 203-528-1, see 2-Pentanone EINECS 203-544-9, see 1-Nitropropane EINECS 203-545-4, see Vinyl acetate EINECS 203-548-0, see 2,4-Dimethylpentane EINECS 203-550-1, see 4-Methyl-2-pentanone EINECS 203-558-5, see Diisopropylamine EINECS 203-560-6, see Isopropyl ether EINECS 203-561-1, see Isopropyl acetate EINECS 203-564-8, see Acetic anhydride EINECS 203-571-6, see Maleic anhydride EINECS 203-576-3, see m-Xylene EINECS 203-598-3, see Bis(2-chloroisopropyl) ether EINECS 203-604-4, see 1,3,5-Trimethylbenzene EINECS 203-608-6, see 1,3,5-Trichlorobenzene EINECS 203-620-1, see Diisobutyl ketone EINECS 203-621-7, see sec-Hexyl acetate EINECS 203-623-8, see Bromobenzene EINECS 203-624-3, see Methylcyclohexane EINECS 203-625-9, see Toluene EINECS 203-628-5, see Chlorobenzene EINECS 203-630-6, see Cyclohexanol EINECS 203-632-7, see Phenol EINECS 203-686-1, see Propyl acetate EINECS 203-692-4, see Pentane EINECS 203-694-5, see 1-Pentene EINECS 203-695-0, see cis-2-Pentene EINECS 203-699-2, see Butylamine EINECS 203-713-7, see Methyl cellosolve EINECS 203-714-2, see Methylal EINECS 203-716-3, see Diethylamine EINECS 203-721-0, see Ethyl formate EINECS 203-726-8, see Tetrahydrofuran EINECS 203-729-4, see Thiophene EINECS 203-767-1, see 2-Heptanone EINECS 203-772-9, see Methyl cellosolve acetate EINECS 203-777-6, see Hexane EINECS 203-799-6, see 2-Chloroethyl vinyl ether EINECS 203-804-1, see 2-Ethoxyethanol EINECS 203-806-2, see Cyclohexane EINECS 203-807-8, see Cyclohexene EINECS 203-809-9, see Pyridine EINECS 203-815-1, see Morpholine EINECS 203-839-2, see 2-Ethoxyethyl acetate EINECS 203-870-1, see Bis(2-chloroethyl) ether EINECS 203-892-1, see Octane EINECS 203-893-7, see 1-Octene EINECS 203-905-0, see 2-Butoxyethanol EINECS 203-913-4, see Nonane EINECS 203-920-2, see Bis(2-chloroethoxy)methane EINECS 203-967-9, see Dodecane EINECS 204-066-3, see 2-Methylpropene EINECS 204-112-2, see Triphenyl phosphate EINECS 204-211-0, see Bis(2-ethylhexyl) phthalate EINECS 204-258-7, see l,3-Dichloro-5,5-dimethylhydantoin... [Pg.1482]

R=methyl R=ethyl R=cyclohexyl R=isopropyl R=2-chloroethyl R= 1,1-pentafluoro-phenylethyl R=n-propyl R=n-butyl R=sec-butyl R=isobutyl... [Pg.71]

A clean and dry 20-gallon glass lined tank was charged with 19 L of water and 4.44 kg of sodium carbonate, after the carbonate had dissolved 4.29 kg (17.5 moles) of 5-(2-chloroethyl)-6-chloro-oxindole and 3.62 kg (16.5 moles) of 1-(l,2-benzisothiazol-3-yl)piperazine were added. The aqueous slurry was heated to reflux and the temperature maintained for 14 hours. When the reaction was complete the solution was cooled to 20°C and filtered. The wet product was reslurried in 23 L of isopropyl alcohol at room temperature for 2 hours. The product was collected by filtration on 2 large Buchner funnels, each was washed with 3.4 L of fresh isopropyl alcohol. The product was vacuum dried at 30° to 40°C. until no isopropyl alcohol remained, giving 5.89 kg (86.4% yield) of the desired free base which matched a standard sample by high performance liquid chromatography (HPLC). [Pg.3554]

Z (CH3CH2)20—AICI3 14.4. (a) methoxyethene methyl vinyl ether (b) ethyl isopropyl ether 2-ethoxypropane (c) 2-chloroethyl methyl ether l-chloro-2-methoxyethane (d) 2-ethoxy-2,3-dimethylpen-tane (e) 1,1-dimethoxycyclopentane (f) tran.s-2-methoxycyclohexanol (g) cyclopropyl methyl ether methoxycyclopropane. 14.6. (a) dihy-dropyran (b) 2-chloro-1,4-dioxane (c) 3-isopropylpyran (d) trans-2,3-diethyloxirane or trans-3,4-epoxyhexane (e) 3-bromo-2-ethoxyfuran ... [Pg.1262]

Chloroethyl)- gave 2-(2-bromoethyl)- (NaBr, Me2NCHO, 70°C, 12 h 88%) or 2-(2-iodoethyl)-5-isopropyl-3,6-dimethoxy-2-methyl-2,5-dihydropyrazine (likewise but Nal 88%).1608... [Pg.181]

C10H14CIN N-ethyl-N-(2-chloroethyl)aniline 92-49-9 25.00 1.0345 2 20100 C10H14O2 3-methyl-6-isopropyl-1,2-benzenediOl 490-06-2 21.73 1.0338 2... [Pg.253]

Besides Ampicillin, 1-chloroalkyl alkyl carbonates and particularly 1-chloroethyl ethyl carbonate (CEEC), 1-chlo-roethyl isopropyl carbonate (CEIC), 1-chloroethyl cyclohexyl carbonate (CECC) and chloromethyl ethyl carbonate (CEMC), have been proposed to modify numerous compounds. Among the many types of prodrugs patented which require this method, there are examples of ... [Pg.33]

Synonyms 2-(p-Butyl phenoxy)-l-methylethyl-2-chloroethylsulfite 2-(p-Butyl phenoxy) isopropyl-2-chloroethyl sulfite Aracide Aramit Aratron Ortho-mite Chemical Structure ... [Pg.167]

Oser BL and Oser M (1960) 2-(p-tert-Butylphenoxy(isopropyl 2-chloroethyl sulfite (Aramite). I. Acute, subacute, and chronic oral toxicity. Toxicology and Applied Pharmacology 2 441-457. [Pg.168]

ETHANOL, 2-CHLORO-, ESTER WITH 2-(P-TERT-BUTYLPHENOXY)-1-METH YLETHYL SULFITE ETHANOL, 2-CHLORO-, 2- P-T-BUTYLPHENOXY)-1-METHYLETHYL SULFITE ETHANOL. 2-CHLORO-. 2-(P-T-BUTHYLPHENOXY)-1-METHYLETHYL SULFITE SULFUROUS ACID, 2-CHLOROETHYL 2-t4-(1,1-DIMETHYLETHYL)PHENOXY]-1-METHYLETHYL ESTER 2-CHLOROETHYL SULPHITE OF 1-(P-T-BUTYLPHENOXY)-2-PROPANOL 2-(P-BUTYLPHENOXY)-1-METHYLETHYL 2-CHLOROETHYL SULFITE 2-(P-BUTYLPHENOXY)ISOPROPYL 2-CHLOROETHYL SULFITE 2-(P-T-8UTYLPHENOXY)-1-METHYLETHYL 2 -CHLOROETHYL SULPHITE 2-(P-T-BUTYLPHEN0XY)-1-METHYLETHYL 2-CHLOROETHYL ESTER OF SULPHUROUS ACID 2-(P-T-BUTYLPHENOXY)-1-METHYLETHYL SULPHITE OF 2-CHLOROETHANOL 2-(P-T-8UTYLPHENOXY)ISOPROPYL 2 -CHLOROETHYL SULPHITE 2-(P-TERT-BUTYLPHENOXY)-1-METHYLETHYL 2-CHLOROETHYL ESTER SULFUROUS ACID 2-(P-TERT-BUTYLPHENOXY)ISOPROPYL 2-CHLOROETHYL SULFITE 2-CHLOROETHYL 1-METHYL-2- P-T-BUTYLPHENOXY)ETHYL SULFATE 2-(4-T-BUTYLPHENOXY)ISOPROPYL-2-CHLOROETHYL SULFITE... [Pg.3]

See other pages where 2- isopropyl-2 -chloroethyl is mentioned: [Pg.476]    [Pg.163]    [Pg.250]    [Pg.348]    [Pg.175]    [Pg.359]    [Pg.369]    [Pg.26]    [Pg.3553]    [Pg.401]    [Pg.288]    [Pg.576]    [Pg.63]    [Pg.98]    [Pg.1294]    [Pg.1556]    [Pg.457]    [Pg.359]    [Pg.163]    [Pg.143]    [Pg.98]    [Pg.373]   


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2- isopropyl-2 -chloroethyl sulfite

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