Ultrasound intravascular

C. L. de Korte, G. Pasterkamp, A. F. van der Steen, H. A. Woutman and N. Bom, Characterization of plaque components with intravascular ultrasound elastography in human femoral and coronary arteries in vitro, Circulation, 2000, 102, 617-623. 

Surruys PW, Degertekin M, Tanabe K, et al. Intravascular ultrasound findings in the multicenter randomized, double-blind RAVEL trial. Circulation 2002 106 798-803. 

Kobayashi Y, Honda Y, Christie LG, et al. Long-term vessel response to a self-expanding coronary stent a serial volumetric intravascular ultrasound analysis from the ASSURE trial. J Am Coll Cardiol 2001 1329-1334. 

Transcoronary venous injection is performed with a catheter system threaded percutaneously into the coronary sinus. Initial studies in swine have confirmed the feasibility and safety of this approach [121]. This delivery method has also been used to deliver skeletal myoblasts to scarred myocardium in cardiomyopathy patients [120]. With intravascular ultrasound guidance, this approach allows the operator to extend a catheter and needle away from the pericardial space and coronary artery into the adjacent myocardium. To date, human feasibility studies have had a good safety profile. This technique is limited, however, by coronary venous tortuosity, lack of site specific targeting, and its own technically challenging nature. Unlike the transendocardial approach, in which cells are... 

Fig. 8.2 (A) Intravascular ultrasound (IVUS) image of a coronary artery using Revolution 45 MHz IVUS imaging catheter. (B) Plaque composition imaging using volcano VH IVUS system. Green areas represent Fibrous plaque. Yellow is fibro-fatty areas. Red is the necrotic core and white represents areas of dense calcium...

Mano T, Masuyama T, Yamamoto K, Naito J, Kondo H, Nagano R, Tanouchi J, Hori M, Inoue M, Kamada T. 1996. Endothelial dysfunction in the early stage of atherosclerosis precedes appearance of intimal lesions assessable with intravascular ultrasound. Am Heart J 131 231-238. 

ACS represents a prothrombotic state not just confined to the culprit lesion, with evidence of a pan coronary process and generalized platelet activation. Multiple vulnerable plaques in nonculprit vessels have been identified by angioscopy or intravascular ultrasound in ACS. Protracted treatment with clopidogrel induces antiplatelet activity that provides early benefits, and may limit thrombotic events within the following months. In the CURE study, the curves of major vascular events continue to diverge and showed an additional benefit from one-month follow-up to one year. 

In addition, a recent study in which reconstituted HDL was infused into human subjects after acute coronary syndromes showed a significant reduction in plaque volume in the coronary arteries as assessed by intravascular ultrasound (32). 

Mintz GS, Nissen SE, Anderson WD, et al. American college of cardiology clinical expert consensus document on standards for acquisition, measurement and reporting of intravascular ultrasound studies (IVUS). A report of the American college of cardiology task force on clinical expert consensus documents. J Am Coll Cardiol 2001 37 1478-1492. 

Petronio AS, Amoroso G, Limbruno U, et al. Simvastatin does not inhibit intimal hyperplasia and restenosis but promotes plaque regression in normocholesterolemic patients undergoing coronary stenting a randomized study with intravascular ultrasound. Am Heart J 2005 149 520-526. 

Mintz GS, Popma JJ, Pichard AD, et al, Arterial remodeling after coronary angioplasty a serial intravascular ultrasound study, Circulation 1996 94 35—43. 

Takagi T Yamamuro A, Tamita K, et al, Pioglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with type 2 diabetes mellitus an intravascular ultrasound scanning study. Am Heart J 2003 I46 E5. 

SousaJE, Costa MA, Abizaid AC, et al, Sustained suppression of neointimal proliferation by sirolimus-eluting stents. One-year angiographic and intravascular ultrasound follow-up. Circulation. 2001 104 2007-201 I. 

Kwok OH, Chow WH, Law TC, et al. First human experience with angiopeptin-eluting stent a quantitative coronary angiography and three-dimensional intravascular ultrasound study. Catheter Cardiovasc Interv2005 66(4) 54l-546. Nakamura M, Wada M, Hara H, et al. Angiographic and clinical outcomes of a pharmacokinetic study of sirolimus-eluting stents lesson from restenosis cases. Circ J 2005 69(10) ... 

Hong MK, Mintz GS, Lee CW, et al, Paclitaxel coating reduces in-stent intimal hyperplasia in human coronary arteries a serial volumetric intravascular ultrasound analysis from the Asian Paclitaxel-Eluting Stent Clinical Trial (ASPECT). Circulation 2003 107(4/517-520. 

Similar studies have used intravascular ultrasound (IVUS) at six-month follow-up to evaluate differences in target-lesion healing and have found less intimal hyperplasia and late lumen loss due to increased plaque burden in patients who had received DES without ICB for the treatment of BMS ISR (41). On the other hand, other IVUS-guided studies have described a significant black-hole phenomenon in patients who have undergone ICB. The black hole, a homogeneous, echolucent intraluminal entity depicted on IVUS, is felt to be a result of an impaired response to endothelial injury and an altered molecular proliferative response (Fig. 2). This intraluminal tissue, which accounted for —50% of the neo-intimal growth in areas of restenosis after radioactive stent... 

Schiele TM, Konig A, Rieber J, et al. Sirolimus-eluting stent implantation and beta-irradiation for the treatment of in-stent restenotic lesions comparison of underlying mechanisms of acute gain and late loss as assessed by volumetric intravascular ultrasound, Am Heart J 2005 I 50(2) 351 —357. 

Costa MA, Sabate M, Angiolillo DJ, et al, Intravascular ultrasound characterization of the "black hole" phenomenon after drug-eluting stent implantation, Am J Cardiol 2006 97(2) 203-206. 

Sabate M, Serruys PW, van der Giessen WJ, et al. Geometric vascular remodeling after balloon angioplasty and /3-radiation therapy a three-dimensional intravascular ultrasound study. Circulation 1999 100 1 182-1 188. 

Ahmed JM, Mintz GS, Weissman NJ, et al, Mechanism of lumen enlargement during intracoronary stent implantation an intravascular ultrasound study. Circulation 2000 102 7-10. 

Limpjankit T, Waksman R, Yock PG, et al, Intravascular ultrasound volumetric assessment of intimal hyperplasia in stents treated with intracoronary radiation. Am J Cardiol 1999 84 850-854. 

Tanabe K, Serruys PW, Degertekin M, et al. Chronic arterial responses to polymer-controlled paclitaxel-eluting stents comparison with bare metal stents by serial intravascular ultrasound analyses data from the randomized TAXUS-II trial. Circulation 2004 109(2) 196-200. 

Hausmann D, Johnson JA, Sudhir K, et al. Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia correlation with high density lipoproteins, J Am Coll Cardiol I 996 27 1 562-1 570. 

Rioufol G, Finet G, Ginon I, et al. Multiple atherosclerotic plaque rupture in acute coronary syndrome a three-vessel intravascular ultrasound study, Circulation 2002 106 ... 

Structure of BRILLIANT EU. Abbreviations IVUS, intravascular ultrasound MACE, major adverse cardiac events MLA, minimal luminal area MLD, minimal luminal diameter QCA, qualitative coronary angiography SAT, subacute stent thrombosis TLR, target lesion revascularization TVF, target vessel failure TVR, target vessel revascularization. 

Sierevogel MJ, Pasterkamp G, Velema E, et al. Oral matrix metalloproteinase inhibition and arterial remodeling after balloon dilation—an intravascular ultrasound study in the pig. Circulation 2001 103 302-307. 

---