Interrenal

Gravel, A. and Vijayan, M.M. (2006). Sahcylate disrupts interrenal steroidogenesis and brain glucocorticoid receptor expression in rainbow trout. Toxicology Science 93, 41-49. 

Hontela, A., Daniel, C., and Rasmnssen, J.B. (1997). Structural and functional impairment of the hypothalamo- pituitary-interrenal axis in hsh exposed to bleached kraftmill effluent in the St. Maurice River, Quebec. Ecotoxicology 6, 1-12. 

Holland, J.W., T.G. Pottinger and C.J. Secombes. Recombinant interleukin-1 beta activates the hypothalamic-pituitary-interrenal axis in rainbow trout, Oncorhynchus mykiss. J. Endocrinol. 175 ... 

References include investigations of adrenal medulla and cortex, as well adrenal (interrenal, suprarenal) tissue of non-mammalian vertebrates. Studies using cells of the adrenal medulla are indicated by an asterisk. 

Balm, P.H.M. and T.G. Pottinger. Corticotrope and melanotrope POMC-derived peptides in relation to interrenal function during stress in rainbow trout (Oncorhynchus mykiss). Gen. Comp. Endocrinol. 98 279-288, 1995. 

Barry, T.P., M. Ochial and J.A. Malison. In vitro effects of ACTH on interrenal corticosteroidogenesis during early larval development in rainbow trout. Gen. Comp. Endocrinol. 99 382-387, 1995. 

Benguira, S. and A. Hontela. Adrenocorticotrophin- and cyclic adenosine 3 -5 -monophosphate-stimulated cortisol secretion in interrenal tissue of rainbow trout exposed in vitro to DDT compounds. Environ. Toxicol. Chem. 19 842-847, 2000. 

Girard, C., J.C. Brodeur and A. Hontela. Responsiveness of the interrenal tissue of yellow perch (Perea flavescens) from contaminated sites to an ACTH challenge test in vivo. Can. J. Fish. Aquat. Sci. 55 438-450, 1998. 

Hontela, A., C. Daniel and A.C. Ricard. Effects of acute and subacute exposures to cadmium on the interrenal and thyroid function in rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 35 171-182,1996. 

Ilan, Z. and Z. Yaron. Suppression by organochlorines of the response to adrenocorticotropin of the interrenal tissue in Sarotherodon Aureus (Teleostei). J. Endocrinol. 87 185-193, 1980. 

Jiang, J., G. Young, T. Kobayashi and Y. Nagahama. Eel (Anguilla japonica) testis 1 lB-hydroxylase gene is expressed in interrenal tissue and its product lacks aldosterone synthesizing activity. Mol. Cell. Endocrinol. 146 207-211, 1998. 

Jonsson, C.-J., B.O. Lund, B. Brunstrom and I. Brandt. Toxicity and irreversible binding of two DDT metabolites 3-methylsulfonyl-DDE and o,//-DDD in adrenal interrenal cells in birds. Environ. Toxicol. Chem. 13 1303-1310, 1994. 

Leblond, V. and A. Hontela. Effects of in vitro exposures to cadmium, mercury, zinc, and l-(2-chlorophenyl)-l-(4-chlorophenyl)-2,2-dichloroethane on steroidogenesis by dispersed interrenal cells of rainbow trout (Oncorhynchus mykiss). Toxicol. Appl. Pharmacol. 157 16—22, 1999. 

Patino, R., C.S. Bradford and C.B. Schreck. Adenylate cyclase activators and inhibitors, cyclic nucleotide analogs, and phosphatidylinositol effects on interrenal function of Coho salmon (Oncorhynchus kisutch) in vitro. Gen. Comp. Endocrinol. 63 230-235, 1986. 

Quabius, E.S., P.H.M. Balm and S.E. Wendelaar Bonga. Interrenal stress responsiveness of tilapia (Oreochromis mossambicus) is impaired by dietary exposure to PCB126. Gen. Comp. Endocrinol. 108 472-482, 1997. 

Wilson, J.M., M.M. Vijayan, C.M. Kennedy and G.K. Iwama. /3-Naphthoflavone abolishes interrenal sensitivity to ACTH stimulation in rainbow trout. J. Endocrinol. 157 63—70, 1998. 

Hontela, A. Interrenal dysfunction in fish from contaminated sites in vivo and in vitro assessment. Environ. Toxicol. Chem. 17 44—48, 1998. 

In bony fishes, corticosteroids are secreted from the interrenal tissues (analogous to the adrenal cortex) located in the head kidney region121 182. Cortisol is the major steroid released from these cells in response to neuroendocrine stimulation emanating from the hypothalamus and the pituitary (see Chapter 12). The release of cortisol in response to stress has been characterized in several species and also in response to different stressors and this topic has been extensively reviewed1011 70 182. Cortisol... 

Sangalang, G.B. and J.F. Uthe. Corticosteroid activity, in vitro, in interrenal tissue of Atlantic salmon (Salmo salar) parr. 1. Synthetic profiles. Gen. Comp. Endocrinol. 95 273-285, 1994. 

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