Interleukin-8, mRNA expression

Pechkovsky DV, Zissel G, Ziegenhagen MW, et al. Effect of proinflammatory cytokines on interleukin-8 mRNA expression and protein production by isolated... 

Ryan, C.A., et al., Inducible interleukin 4 (IL-4) production and mRNA expression following exposure of mice to chemical allergens. Toxicol. Lett., 94, 1, 1998. 

Lee, W.Y, Fischer, S.M., Butler, A.P. Locniskar, M.F. (1993) Modulation of interleukin-la mRNA expression in mouse epidermis by tumor promoters and antagonists. Mol. Carcinog., 7, 26-35... 

Rabinovitch, A., Suarez-Pinzon, W. L., Sorensen, O., Bleackley, R. C., Power, R. F. and Rajotte, R. V. (1995). Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft.Transplantation 60, 368-374. 

Li, Y., Liu, L., Kang, J., Sheng, J.G., Barger, S.W., Mrak, R.E., Griffin, W.S. (2000b). Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression. J. Neurosci. 20 149-55. 

Klein, S. A., Ottman, O. G., Dobmeyer, T. S., Pape, M., Weidman, E., Hoelzer, D., and Kalina, U. (1999). Quantification of human interleukin 18 mRNA expression by competitive reverse transcriptase ptolymerase chain reaction. Cytokine 11 451. 

A. B. and Durham, S.R (1993). Increases in activated T lymphocytes, eosinophils and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics. Am. J. Respir. Cell Mol. Biol. 8, 35-42. 

Substance P content has been shown to be present at high levels in nerves subtending inflamed organs or tissues. For example, an inflammatory cytokine, interleukin 1 8 (IL-1/3), has been found to elevate substance P content and PPT-I mRNA expression in rat superior cervical ganglion cells in culture (Jonakait et al., 1991). This eflFect has also been documented in vivo-, increased levels of PPT-I mRNA and substance P product have... 

Navikas V, Matusevicius D, Soderstrom M, et al. Increased interleukin-6 mRNA expression in blood and cerebrospinal fluid mononuclear cells in multiple sclerosis. J Neurolmmuno 1996 64 63-9. 

Appel, K., Buttini, M., Sauter, A., and Gebicke-Haerter, P. J, Cloning of rat interleukin-3 receptor P-subunit from cultured microglia and its mRNA expression in vivo, J. Neurosci., 15, 5800, 1995. 

Buchan, G., Barrett, K., Turner, M., Chantry, D., Maini, R. N., and Feldmann, M. Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis Prolonged production of IL-1 alpha. Clin. Exp. Immunol 73, 449-455 (1988). 

Carman-Krzan, M., Vige, X. and Wise, B.C. (1991) Regulation by interleukin-1 of nerve growth factor secretion and nerve growth factor mRNA expression in rat primary astroglial cultures. J. Neurochem. 56 636-643. 

Rivera, S., Gold, S.J. and Gall, C.M. (1994) Interleukin-lb increases basic fibroblast growth factor mRNA expression in adult rat brain and organotypic hippocampal cultures. Mol. Brain Res. 27 12-26. 

Very low levels of PDS mRNA expression have been reported in tissues such as lung, endometrium, prostate, and testis (Lacroix et ai, 2004). Pendrin protein expression has also been documented in Sertoli cells and the lung (Lacroix et ai, 2004 Pedemonte et aL, 2007). It is currently unknown whether pendrin has a physiological role in these tissues. In the lung, pendrin protein expression is upregulated by interleukin 4 (lL-4) and it has been proposed to play a role in the transport of thiocyanate (Pedemonte et ai, 2007). 

Cassatella MA, Gasperini S, Bovolenta C, Calzetti F, Vollebregt M, Scapini P, Marchi M, Suzuki R, Suzuki A, Yoshimura A Interleukin-10 (lL-10) selectively enhances C1S3/SOCS3 mRNA expression in human neutrophils Evidence for an IL-lO-induced pathway that is independent of STAT protein activation. Blood 1999 94 2880-2889. 

Pellett, P.L., Protein requirements in humans. Am J Clin Nutr, 51, 723, 1990. Fischer, C.P, Plomgaard, P, Hansen, A.K., Pilegaard, H., Saltin, B., and Pedersen, B.K., Endurance training reduces the contraction-induced interleukin-6 mRNA expression in human skeletal muscle. Am J Physiol Endocrinol Metab, 287, El 189, 2004. 

In the adipose tissue, the adiponectin and the TNFa are important control factors through the MCFA GPR84 systemthat is involved in the use of excess calories and in the control of the insulinresistance syndrome. In the inflammation process of the adipose tissue, which also increases the GPR84 mRNA expression, some specific products such as tumor necrosis factor (TNF)-a, interleukin-6 (IL-6) and adiponectin are secreted. 

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