Interaction of nitric oxide

Chiavegatto S, Nelson RJ (2003) Interaction of nitric oxide and serotonin in aggressive behavior. Horm Behav 44 233-241... 

Stamler, IS. Redox signalling nitrosylation and related target interactions of nitric oxide (1994) CeU 78, 931-936... 

Griffith el al. (Ill, 112) have shown that the blue compounds obtained by the interaction of nitric oxide and nickel carbonyl in the presence of water or an alcohol (68) have the general formula Ni(NO)(OR)3, and are probably tetrahedral. The N—0 stretching frequency of 1828 cm-1 in Ni(NO)(OH)3 indicates coordination of N0+ the spectra show absorption at 15,500 cm-1, in agreement with other such complexes, but the magnetic moment of Ni(NO)(OH)3 is only 2.97 B.M., which indicates considerable distortion. 

The interactions of nitric oxide with oxygen help explain the shott half-life of nittic oxide as a messenger and implicate nitric oxide as a major participant in free radical injury. Oxygen is required for the synthesis of nitric oxide and therefore must be present in tissue in substantially higher concentrations than... 

Hyman, M. R., and Arp, D. J. (1991). Kinetic analysis of the interaction of nitric oxide with the membrane-associated, nickel and iron-sulfur-containing hydrogenase from Azotobacter vinelandii. Biochim. Biophys. Acta 1076, 165-172. 

Klamer D., Zhang J., Engel J. A., and Svensson L. (2005). Selective interaction of nitric oxide synthase inhibition with phencyclidine behavioural and NMDA receptor binding studies in the rat. Behav. Brain Res. 159 95-103. 

Brenman JE, Chao DS, Gee SH, McGee AW, Craven SE, Santillano DR, Wu Z, et al. (1996) Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha 1-syntrophin mediated by PDZ domains. Cell 84 757-67 Broillet MC, Firestein S (1996) Direct activation of the olfactory cyclic nucleotide-gated channel through modification of sulfhydryl groups by NO compounds. Neuron 16 377-85... 

Glutathionylated proteins can be formed by the interaction of nitric oxide and protein thiols. For example, exposure of mitochondria to NO can lead to the formation of peroxynitrite, an oxidant, that can cause protein glutathionylation. Protein glutathionylation may also occur via the formation of a nitroso thiol protein (PrSNO) followed by the glutathionylate anion displacement of the nitroxyl anion (NO-) by GSH to form protein glutathionylation as shown in Figure 18.13. 

The interaction of nitric oxide and hydrogen was first examined by Green and Hinshelwood . In the region of 1000-1100 °K it was found to be a termolecular reaction proceeding in accordance with the equation... 

The spontaneous interaction of nitric oxide with QFjAsF is in harmony with the ionization potentials (/(NO) 2l3 kcal moF, /(QFfi) = 230 kcal moF ) and lattice energies (LE-(CftFjAsFfe) =s -115 kcalmoF, LE NOAsF ) = -130 kcal moF ). 

And this provided a clean synthesis for the NOMFg salts (see Ref. 23) which could not be obtained cleanly from the interaction of nitric oxide with the hexafluorides, since the NOMFe salts (M = Ir, Pt) were able to oxidize NO to produce (NO)2 MFe. But F2 was not the only gaseous product of the ONF/MFe reactions, the new nitrogen oxide trifluoride also being a product, which was present in good yield in the IrFe reaction (see Ref. 25), ideally ... 

Torres, J., Cooper, CE, and Wilson, MT. 1998. A common mechanism for the interaction of nitric oxide with the oxidized binuclear centre and oxygen intermediates of cytochrome c oxidase. 7 Biol Chem 273 8756-8766. 

Ioannidis, N., Schansker, G., Barynin, V. V. and Petrouleas, V. Interaction of nitric oxide with the oxygen evolving complex of photosystem II and manganese catalase a comparative study. Journal of Biological and Inorganic Chemistry 5 354-563 2000. 

Nitric oxide is synthesized from arginine in an NADPH-dependent reaction catalyzed by nitric oxide synthase (Fig. 22-31), a dimeric enzyme structurally related to NADPH cytochrome P-450 reductase (see Box 21-1). The reaction is a five-electron oxidation. Each subunit of the enzyme contains one bound molecule of each of four different cofactors FMN, FAD, tetrahydrobiopterin, and Fe heme. NO is an unstable molecule and cannot be stored. Its synthesis is stimulated by interaction of nitric oxide synthase with Ca -calmodulin (see Fig. 12-21). 

Interaction of nitric oxide with ammonia can be highly exothermic. When Reactions 6 and 7 are compared on a C vs. N basis, the heat effect is of the same magnitude as hydrocarbon oxidation (173 kcal per NO by Reaction 6 vs. 160 kcal for typical hydrocarbon oxidation). 

TABLE II Biochemical Interactions of Nitric Oxide (NO) and Related Species... 

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