Integrated process design

Titchener-Hooker, N. J., Gritsis, D., Mannweiler, K., Olbrich, R., Gardiner, S. A. M., Fish, N. M., and Hoare, M., Integrated process design for producing and recovering proteins from inclusion bodies, BioPharm, July/Aug., 34,1991. 

Applications — Integrated Process Design and Operation of Sewers... 

As integrated process designs continued to gain acceptance owing to their improved economics, the process control community also became aware of the distinct challenges posed by the operation of such plants, and a number of research studies ensued. 

Today, the field of integrated process design is an active area of scientific research with immediate impact on the engineering practice. Methods accepted by the process-engineering community are described briefly below. 

Integrated process design is the paradigm for designing efficient and sustainable processes. Key features are ... 

The systematic methods and the analysis tools of integrated process design can be applied to any type of chemical process industries, from refining to biotechnologies, as well as to new or revamped projects. 

Chapter 1 Introduction presents the concepts and metrics of sustainable development, as well as the framework of an integrated process design by means of two interlinked activities, process synthesis and process integration. 

Moreover, these optimization formulations can easily be coupled to other process. systems such as heat integration and. separation sequences. As a result, they provide a framework for integrated process design. This strategy is illustrated with detailed examples. Finally, limitations of the current approach are summarized and topics for future work are outlined. 

The case study of vinyl acetate synthesis emphasises the benefits of an integrated process design and plantwide control strategy based on the analysis of the Reactor / Separation / Recycles structure. The core is the chemical reactor, whose behaviour in recycle depends on the kinetics and selectivity of the catalyst, as well as on safety and technological constraints. Moreover, the recycle policy depends on the reaction mechanism of the catalytic reaction. 

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