Installation and commissioning

This shall be preferably done by the vendor and shall be included in the purchase 

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Ease of installation and commissioning is another reason for gas turbine use. A gas turbine unit can be tested and packaged at the factory. Use of a unit should be carefully planned so as to cause as few start cycles as possible. Frequent startups and shutdowns at commissioning greatly reduce the life of a unit. 

You should develop a documented procedure for the facility planning activity that will ensure the provision of adequate information on which to base plant design decisions. The procedures should provide for a separate development plan with allocation of responsibilities for the various tasks to be undertaken and should cover the layout, specification, procurement, installation, and commissioning of the new or revised plant. 

Project plans for the installation and commissioning of new plant should be prepared in order to ... 

Optical fibres are not yet very much in use, but there is no interference between them and electrical signals of any sort. For this reason their use will probably become more widespread. Line-of-sight optical signals require that no obstruction is inserted at any time. Such points are easily noticed when installing and commissioning, but are not so obvious if a malfunction occurs at a later date. 

To keep the installation and commissioning times to a minimum, the entire unit is preassembled at the machine builder s factory. As far as possible, the necessary auxiliary equipment is also htted. For the multiplex head, this means prefitting of the hydraulic pipework from the cylinders to the hydraulic power unit. 

Ensure feat high-pressure oxygen systems are designed, constructed, installed and commissioned by competent people wife specialized knowledge of the subject. 

No general allowance was made for site restoration, since this cost is highly variable. The cost of purchasing, installing, and commissioning a 250-ton/day mobile ChemTech soil treatment plant is estimated to be approximately 1.5 million (U.S. dollars, 1997). 

In the majority of cases, the application of a computer system to pharmaceutical manufacturing is part of a capital investment involving other items of production plant equipment and a wide range of contracted design, installation, and commissioning activities carried out by appropriate engineering disciplines. 

API produced by the commercial manufacturer. This timing, which helps to simplify the dialogue with the FDA, is not always achievable if the putative commercial site requires an investment in specialized equipment which takes a long time to deliver, install, and commission. It can be seen from this that investment in the manufacturing plant needs to be recognized and addressed early in the development of the final process step. Situations such as this demonstrate why great importance needs to be attached to developing the last process step as soon as possible. 

In the late 1990s he was involved in the installation and commissioning of process scale HPLC at Zeneca Pharmaceuticals. During 18 years with CRB, ICI, Zeneca and Avecia he was instrumental in establishing the technique of preparative HPLC within the company and served 11 years as the secretary of the company s Process Scale Chromatography Group. 

It has been constructed in a clean area adjacent to the SNF area and will be lifted into position using the existing crane. The cover will be installed and commissioned before the end of 2004. 

Formal qualification is conducted against the GxP aspects of the IPC application, identified by the Risk Assessment. The SAT scope covers the installation and commissioning of the system. 

Wooton AB. Design, installation and commissioning of photostabUity test cabinets, IBC Technical Services Ltd. Conference on Stability Testing Design and Interpretation of Data for International Registration of Pharmaceuticals, London, April 27-28,1994. 

Most basic validation activities within the cGMP pilot plant are identical to those expected in practice in a manufacturing facility. A validation master plan should be developed that addresses the design specifications and qualification, installation qualification (IQ), operational qualification (OQ), and performance qualification (PQ) of all major utility systems, process equipment, and computer control systems. Installation and commissioning data should be retained as part of an engineering documentation package. A workable... 

Most solvents can be removed readily from process streams by distillation on scale. Distillation of a product can be very labor-intensive and may require specialized equipment. Once suitable equipment has been installed and commissioned, processing can be relatively trouble-free, especially if the appropriate control equipment is used. Many high-molecular weight molecules are too unstable to distill, making crystalline intermediates and products necessary for convenient operations. 

Rose, D., 1985, Guidelines for the processing and aseptic packaging of low acid foods. Part 1. Principles of design installation and commissioning. Campden Food Preservation Research Association. Chipping Campden. 

With most specifications there are some key aspects that should be clearly stated or defined, the omission of which can cause embarrassment, delay and extra costs at a later date e.g. at the factory inspection, during installation and commissioning. A well-designed data sheet to accompany the specification will do much to avoid ambiguity or the omission of requirements. The data sheet should comprise two parts, a part completed by the purchaser to define the requirements and a corresponding part for the manufacturer to state what is offered. 

Before the equipment is delivered to the site it will normally undergo the type and routine tests in the factory. These tests are often referred to as the factory acceptance tests (FAT). Some documents are required before the FAT and others afterwards. Those required before are usually the inspection reports as part of the quality assurance plan, instruction manuals for transportation, storage, installation and commissioning routine maintenance. 

Maintenance during installation and commissioning Project management planning and control... 

FRAMATOME ANP, France. FRAMATOME has overall responsibility for all activities needed to implement the module Ml systems including documentation, design, manufacturing, and participation in installation and commissioning, and personnel training. 

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