Insect peptides

Kuniyoshi H., Nagasawa H., Ando T., Suzuki A., Nachman R. J. and Holman G. M. (1992b) Cross-reactivity between pheromone biosynthesis activating neuropeptide (PBAN) and myotropic pyrokinin insect peptides. Biosci. Biotech. Biochem. 56,167-168. 

Selective inhibition of trypsins by insect peptides role of P6-P10 loop... 

I. Insect peptide nomenclature follows the rules prescribed in Raina and GSde, Insect Biochem, 1988,18,785-787. 

The elucidation of the primary structures of proctolin (22) and AKH (2Q), signaled the beginning of the structural identification of insect neuropeptides. These relatively small peptides (pentapeptide proctolin and decapeptide AKH) remained the only known insect peptide sequences for a number of years until, in the early 1980 s, accumulated technical advances in peptide isolation and microsequencing techniques facilitated the analysis of insect peptides (8-12 ... 

Neuroendocrine control of invertebrate development was first demonstrated by Kopec CL2) with neck ligation and brain extirpation-reimplantation studies using the gypsy moth, Lymantria dispar (Lepidoptera Lymantriidae). His demonstration of a "pupation factor", origmating in the bi in, provided the impetus for identification of numerous invertebrate physiological processes controlled by peptide neurohormones (3.41 In insects, identified processes now number over thirty (5). Knowledge of these processes has provided for the development of bioassays used in the isolation of neuropeptides. Since 1975, over fo insect peptide neurohormones have been isolated and sequenced (5-81... 

At present, the pyrokinins make up a small family of myotropic insect peptides which share the common C-terminal pentapeptide C-terminal sequence Phe-X-Pro-Arg-Leu-NH2 (X - Thr, Val, Ser). ... 

Sequence homology has been noted previously (17) between the N-terminus of Hez-PBAN and insulin-like growth factor II, and the C-terminus with the insect peptide leucopyrokinin (Table II) isolated from cockroach heads. The striking similarity of the first 16 residues of the melanization and reddish colorization hormone (MRCH) of B. mori (18) and Bom-PBAN has led to the suggestion by Kitamura ti 1. (17) that they are identical (Table II), thus implying a dual role for this hormone in the larvae (melanization and reddish colorization) and adult moth (pheromone biosynthesis). 

Nam ST, Kim DH, Lee MB, Nam HJ, Kang JK, Park MJ et al (2013) Insect peptide CopA3-induced protein degradation of p27Kipl stimulates proliferation and protects neuronal cells from apoptosis. Biochem Biophys Res Commun 437 35-40... 

In all of the sequences, there is a pair of aromatic or long-chain aliphaitc residues or both (boxed) separated by a stretch of 12 residues that correspond to Trp and Phe of M13. In addition, there are generally hydrophobic residues at positions equivalent to Phe (which interacts with the carboxyl-terminal domain) and Val" (which interacts with both domains). Sequences skeletal muscle myosin light chain kinase (SK-MLCK) M13 (residues 342 to 367), smooth muscle myosin light chain kinase (SM-MLCK) Ml3 (residues 494 to 513), plasma membrane Ca pump, calspermin, and calcineurin (mouse brain). The mastaporans and mellitin are naturally occurring insect peptides. 

A complete list of sequences for insect peptides up to 1997 is available [10,37], Insect tachykinin-related peptides are given in [73],... 

Insect Peptides encoded by Direct comparison of Matrix deposition 50... 

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