Innovation stem cell research

FFF is still a growing area of research and there are specific fields of application pushing toward innovations both in terms of instrumentation and methodology. For example, MgFFF has been developed specifically for stem cell research, and FIFFF (either FIF FIFFF or AsFlFFF and traditional FIFFF) is driven overall by pharmaceutical-biological applications. In addition, as for others analytical techniques, the new tendency for FFF is toward miniaturization of the instruments. As examples we cite the hollow fiber channel for FIFFF [49], the microthermal unit developed by Janca [50], the microthermal-electrical unit by Gale and coworkers [51], or the SPLITT cells by Hoyos and coworkers [52]. In this regard, we should say that some important but very specialized topics were not reviewed here such as the SPLITT cells and separation channels similar to FFF that are useful for preparative aims, as they would require a detailed description which has already been reported in books and reviews [53,54]. 

The Institute of Cancer Research, Surrey, UK Mitchell J. Frederick Department of Head and Neck Surpfcry, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA Rossella Galli Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy Thomas M. Grogan Medical Innovation, Ventana Medical Systems, Inc, Tucson,... 

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