Infectious disease books

Figure 1.3. Phagocytosis of Staphylococcus aureus by a human neutrophil. Neutrophils were incubated with opsonised S. aureus and fixed after 15 min incubation. The bacterium in the centre has been lysed, and only the cell wall remains. Source Experiment of Bernard Davies and John Humphreys, reproduced with permission from Colour Atlas of Paediatric Infectious Diseases, by Hart and Broadhead (Mosby Year Book Europe).

In Chapter 1, John Lowe details The Role of Medicinal Chemistry in Drug Discovery in the twenty first century. The overview should prove invaluable to novice medicinal chemists and process chemists who are interested in appreciating what medicinal chemists do. In Chapter 2, Neal Anderson summarizes his experience in process chemistry. The perspectives provide a great insight for medicinal chemists who are not familiar with what process chemistry entails. Their contributions afford a big picture of both medicinal chemistry and process chemistry, where most of the readers are employed. Following two introductory chapters, the remainder of the book is divided into three major therapeutic areas I. Cancer and Infectious Diseases (five chapters) II. Cardiovascular and Metabolic Diseases (six chapters) and III. Central Nervous System Diseases (four chapters). 

Loeb M, Fiona Smaill F, Marek Smieja M, editors. Evidence-based infectious diseases. New York Black-well BMJ Books 2004. 

Infectious Diseases (USAMRIID) (USAMRIID. Blue Book. 6ih eel. Fori Dehick, MD April 2005.)... 

Freitas, G. D., Nobrega, A. A., Romano, A. P., Costa, E. G., Tinoco, J. M., Pontes, M. D., Leite, L. S., and Sobel, J. (2008). Novel food implicated in an outbreak of orally-transmitted acute Chagas disease in an Urban area of the Amazon Region, Brazil, 2007. Abstract published in the International Conference on Emerging Infectious Diseases (ICEID)— Program and Abstracts Book, Atlanta, GA, USA. p. 121. 

The contribution of in silico models to the field of drug discovery for infectious diseases has not previously been comprehensively reviewed in the literature. Hence we think this book should be of interest to all those involved in the study and treatment of infectious diseases, including academic researchers, students, industrial and pharmaceutical scientists, and other healthcare professionals. In addition, each chapter in the book covers a unique in silico technique and hence the book could also be used in the microbiology and immunology curricula in medical and graduate schools. 

Committee on Infectious Diseases. In Red Book. 2003 Report of the Committee on Infectious Diseases. 26th ed. Elk Grove Village, IL American Academy of Pediatrics,... 

Part Three is the most extensively modified in the second edition. In the early 1990s asthma was the only disease that was being treated systematically with aerosols. Throughout the decade the concept of treating diabetes with insulin aerosols, cystic fibrosis by gene transfection, and infectious diseases with antimicrobials gained ground. Many of these approaches have yet to be commercial or therapeutic success stories, but by the time this book is in print they may be available to the clinician. Consequently, sections on these topics have been added. 

Mandell, Douglas, and Bennett, eds., Principles and Practice of Infectious Diseases (Churchill Livingstone, Philadelphia, 2000)—This bible of infectious diseases is a must for every infectious diseases practitioner s bookshelf. This book addresses virtually all infectious diseases topics from both a disease- and a pathogen-related perspective. Although the antimicrobial pharmacology component represents only a small portion of... 

Thinking about health, which depends on inherited factors as well as accidents and infectious disease, has to involve at least some basic appreciation of genetics and inheritance of features. Even the Old Testament has some appreciation of the principles and in Thy book all my members were written, which in continuance were fashioned, when as yet there were none of them (Psalms 139 16). The Greeks with their view of philosophy and science, and an interest... 

The history of biological and chemical warfare is lengthy and texts on the subject should be consulted for further details. The focus of this chapter is an extension of the book, foodbome diseases. However, a brief review of this field is instructive. Most of what is presented here relative to terrorist attacks in food, and which has been written about by other authors, has never occurred. This must be viewed as pure speculation extrapolated from the use of chemicals and infectious disease in a military environment. Such speculation, once considered pure fantasy, now has a chilling reality to it based on recent terrorist attacks throughout the world. 

More on anthrax, the Ebola virus, and especially the smallpox virus, are presented in firsthand accounts in Richard Preston s The Demon in the Freezer A True Story, published in 2002. Following the format of his previous book The Hot Zone A Terrifying True Story, Preston interviewed many of the principals involved in the CDC and, in particular, in the U.S. Army Medical Research Institute of Infectious Diseases at Fort Dedrick, Maryland. He gives particulars about the highly successful program to eradicate smallpox, and about still-remaining sources of the stored virus. Included is the fact that genetic modification has produced a new strain that is not affected by conventional vaccinations. 

In his book The Advancing Front of Medicine (1941), George W. Gray wrote of his great admiration of Claude Bernard, a French physician from the late nineteenth century, who many call the father of scientific medicine The driving interest of Claude Bernard s life was the search for an understanding, in terms of physics and chemistry, of those processes, by which we live, by which we become ill, by which we are healed, and by which we die. If we cannot someday treat mental illness with the same effectiveness as we treat infectious diseases, we are all doomed. ... 

This 1962 statement by an eminent Nobel laureate, the Australian physician Sir F. Macfarlane Burnet, is typical. By the end of the twentieth century, he commented, we will see the "virtual elimination of infectious disease as a significant factor in societal life." Further study and publication of infectious disease research, he continued, "is almost to write of something that has passed into history." Seven years later, one of my great-uncle s successors. Surgeon General William Stewart, testified to Congress that "it was time to close the book on infectious diseases." They couldn t have been more wrong. 

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