Inductively coupled plasma, bone

Roberts, N.B, Walsh, H.P.J., Klenerman, L., Kelly, S.A., and Helliwell, T. R. (1996). Determination of elements in human femoral bone using inductively coupled plasma atomic emission spectrometry and inductively coupled plasma mass spectrometry. Journal of Analytical Atomic Spectroscopy 11 133-138. 

Use of inductively coupled plasma-mass spectrometry (1CP-MS) coupled to a laser-ablation sample introduction system (LA-ICP-MS) as a minimally destructive method for chemical characterization of archaeological materials has gained favor during the past few years. Although still a relatively new analytical technique in archaeology, LA-ICP-MS has been demonstrated to be a productive avenue of research for chemical characterization of obsidian, chert, pottery, painted and glazed surfaces, and human bone and teeth. Archaeological applications of LA-ICP-MS and comparisons with other analytical methods are described. 

Shiraishi K, Kawamura H, Tanaka Gl. 1987. Determination of alkaline-earth metals in foetus bones by inductively-coupled plasma atomic-emission spectrometry. Talanta 34 823-827. 

In an earlier paper (13), the INAA procedure was described and compared to the chemical analysis of bone by using inductively coupled plasma emission spectroscopy (ICPES). The ICPES technique required dissolution of the ashed sample before analysis, but otherwise the techniques proved to be quite comparable. In this study, some of the samples were analyzed by using X-ray fluorescence (XRF) to determine whether there was adequate sensitivity for the study of contamination in archaeological bone. 

White, G.W., Gibby, W.A., and Tweedle, M.F. (2006) Comparison of Gd(DTPA-BMA) (Omniscan) versus Gd(HP-D03A) (ProHance) relative to gadoUnium retention in human bone tissue by inductively coupled plasma mass spectroscopy. Investigative Radiology, 41, 272-278. 

BIOLOGICAL PROPERTIES the biological half-life for lead in the bones of humans is 10 yrs can be detected in water by atomic adsorption or by colorimetric analysis or by inductively coupled plasma optical emission spectrometry, dissolved lead by 0.45 micron filtration prior to such analysis... 

Human biological materials to be investigated include (a) hard calcified tissues, e.g. bone, teeth, other calcified formations (b) semi-hard tissue, e.g. hair, nails (c) soft body tissues and (d) various biological fluids and secretions in the human body. The treatment of each of these materials varies from one material to another and, as stated earlier, is often determined by the instrumental method to be employed for measuring the analytical signal, the elements to be determined and the concentration levels at which these are present. For the purposes of this discussion, it shall be generally assumed that the analytical techniques employed include atomic absorption spectrometry both with (F-AAS) as well as with a furnace (GF-AAS), neutron activation analysis (NAA), flame emission spectrometry (FES) voltammetric methods and the three inductively coupled plasma spec-trometric methods viz. ICP-atomic emission spectrometry, ICP-mass spectrometry and ICP-atomic fluorescence spectrometry. The sample preparation of biological methods for all ICP techniques is usually similar (Guo, 1989). 

Mahanti, H.S. and Barnes, R.M. (1983). Dewtermination of major, minor and trace elements in bone by inductively coupled plasma emission.spectrometry. Anal. Chim. Acta 151, 409-417... 

Ti in Bone by Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES) (according to Mahanti and Barnes (14))... 

Latkoczy, C., Prohaska,T., Stingeder, G., andTeschler-Nicola, M. (1998). Strontium isotope ratio measurements in prehistoric human bone samples by means of high-resolution inductively coupled plasma mass spectrometry (HR-ICP-MS). J. Anal. At. Spectrom. 13(6), 561. 

The low concentrations of lead in plasma, relative to red blood cells, has made it extremely difficult to accurately measure plasma lead concentrations in humans, particularly at low PbB concentrations (i.e., less than 20 pg/dL). However, more recent measurements have been achieved with inductively coupled mass spectrometry (ICP-MS), which has a higher analytical sensitivity than earlier atomic absorption spectrometry methods. Using this analytical technique, recent studies have shown that plasma lead concentrations may correlate more strongly with bone lead levels than do PbB concentrations (Cake et al. 1996 Hemandez-Avila et al. 1998). The above studies were conducted in adults, similar studies of children have not been reported. 

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