Indole-3-carbinol

Chemistry and biological properties of polyfunctional indole-3-carbinol derivatives [l-(indol-3-yl)glycerols and related compounds, (3-hydroxytryptamines, and ascorbigens] 95F369. [Pg.249]

D. F. Birt, B. Walker, M. G. Tibbels, and E. Bresnick, Anti-mutagenesis and antipromotion by apigenin, robinctin and indole-3-carbinol. Car.sinogenesis 7 959 (1986). [Pg.219]

Dash wood RH, Arbogst DN, Fong AT, Pereira C, Hendricks JD and Baily GS. 1989. Quantitative interrelationships between aflatoxin B1 carcinogen dose, indole-3-carbinol anto-carcinogen dose, target organ DNA adduction and final tumor response. Carcinogenesis 10 175-181. [Pg.39]

Tanaka T, Mori Y, Morishita Y, Hara A, Ohno T, Kojinna T and Mori H. 1990. Inhibitory effect of sinigrin and indole-3-carbinol on diethylenitrosamine-induced hepatocarcinogenesis in male AC/N rats. Carcinogenesis 11 1403—1406. [Pg.49]

Gao X, Petroff BK, Oluola O, Georg G, Terranova PF, Rozman KK (2002) Endocrine disruption by indole-3-carbinol and tamoxifen blockage of ovulation. Toxicol Appl Pharmacol 183 179-188... [Pg.142]

NT218 Arif, J. M., C. G. Gairola, G. J. Kelloff, R. A. Lubet, and R. C. Gupta. Inhibition of cigarette smoke-related DNA adducts in rat tissues by indole-3-carbinol. Mutat Res 2000 452(1) 11-18. [Pg.351]

Serum sex hormones effect. DION (300 mg androstenedione, 150 mg dehydro-epiandrosterone, 540 mg saw palmetto, 300 mg indole-3-carbinol, 625 mg chrysin, 750 mg Tribulus terrestris), administered daily to healthy 30- to 59-year-old men for 28 days, produced no change in serum concentrations of total T and PSA. DION increased the concentrations of serum androstenedione (342%), free T (38%), DHT (71%), and estradiol (103%). Serum high-density lipoprotein (HDL) cholesterol concentrations were reduced by 5 mg/dL in DION (p < 0.05). Increases in serum free T (r = 0.01), androstenedione (r = 0.01), DHT (r = 0.03), or estradiol (r = 0.07) concentrations in DION were not related to age. The ingestion of androstenedione combined with herbal products increased serum-free T concentrations in older men, but herbal products did not prevent the conversion of... [Pg.475]

Wilker C, Johnson L, Safe S. 1996. Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring. Toxicol Appl Pharmacol 141 68-75. [Pg.707]

Michnovicz JJ, Adlercreutz H, Bradlow HL. Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans. J Natl Cancer Inst 1997 89 718-723. [Pg.191]

Michnovicz JJ, Bradlow HL. Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol. Nutr Cancer 1991 16 59-66. [Pg.191]

Indole-3-carbinol Brassica species Hypocholesterolemic Peluso and Schneeman (1994)... [Pg.282]

Indole 3-carbinol induced a lowering of serum cholesterol levels and the serum LDL-cholesterol/VLDL cholesterol ratio (Mokady, 1992). [Pg.296]

In the fall army worm, Spodopterafrugiperda, sulfoxidation of phorate requires NADPH. It is inhibited by carbon monoxide and piperonyl butoxide, and induced by cytochrome P450 inducers (e.g., indole 3-carbinol and indole 3-acetonitrile) (Yu, 1985). [Pg.148]

Birt, D.R, Walker, B., Tibbels, M.G., and Bresnick, E., Anti-mutagenesis and antipromotion by apigenin, robinetin and indole-3-carbinol, Carcinogenesis, 1, 959-963, 1986. [Pg.75]

Glucobrassicin is a glucosinolate derived from tryptophan, and when it undergoes hydrolysis, the major product is indole-3-carbinol. Diets containing indole-3-... [Pg.111]

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