Individualized therapeutic

In addition to designing an individualized therapeutic regimen to control the progression of rheumatoid arthritis, the clinician must evaluate the presence of comorbidities and implement measures to control the increased risk. 

Translation of Vascular Proteomics into Individualized Therapeutics... 

E = 137keV). The accompanying emission of 7-radiation can be used for scintigraphic imaging but also makes patient isolation necessary. The different half-lifes and /3 -energies allow individual therapeutic demands such as the pharmacokinetics of the tracer molecule, the linear energy transfer of the nuclides or the biodistribution and clearance of the radiolabeled drug to be met. The principles of the application of radioactive materials for therapy are summarized in an excellent review. ... 

Individuals with diabetes should receive medical care from a team coordinated by a physician. Such a physician-coordinated team may include nurses, a dietician and a pharmacist preferably trained as diabetes educators. The management plan should be discussed with the patients and their family, and prescribed as individualized therapeutic plans. 

L Each drug used in the combination regimen should have some individual therapeutic activity against the particular tumor being treated. 

To measure innovation we examined the rate of flow of NCEs into human testing, the earliest point at which reliable information appears outside the pharmaceutical industry and the point at which NCEs enter the regulatory pathway. The rates at which these compounds pass the milestones of the U.S. regulatory pathway (the points of IND filing, NDA submission, and NDA approval) were defined. In addition to the overall analysis, the data were analyzed by individual therapeutic areas. The observed differences between categories of NCEs imply the existence of scientific, industrial, and/or administrative differences between these categories. 

Identify, assess, and solve medication-related problems, and provide clinical judgment as to the continuing effectiveness of individualized therapeutic plans and intended therapeutic outcomes. 

Identifies therapeutic categories or individual therapeutic agents warranting drug utilization evaluation. Develops and conducts drug utilization evaluation in these targeted areas. 

The autologous approach uses tumor cells of the patient for an individualized therapeutic agent This is a cost-intensive procedure which requires the isolation of appropriate tumor cells from tumor material, as well as their cultivation and transfection. The efficacy of the therapeutic agent depends on the quality of the appointed cells (i.e., the expression ofTAA). 

This wide variety of therapeutic options increasingly embedded in multi-disciplinary and modal therapeutic concepts necessitates a differentiated diagnostic work-up to customise individual therapeutic pathways (Fig. 20.3). 

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