INDEX intraperitoneal

Administration of catechol (1.5% in the diet) for 20 weeks induced mild to moderate hyperplasia but no papillomatous lesions in the forestomach in Syrian hamsters. Labelling index, after an intraperitoneal dose of [ HJthymidine, was elevated in the pyloric region, but not in the forestomach or urinary bladder (Hirose et al., 1986). 

The interaction of 1,1,2,2-tetrachloroethane with DNA, RNA and proteins of male Wistar rats and BALB/c mice in vivo was measured 22 h after intraperitoneal injection. The covalent binding index to liver DNA was about 500 (Colacci et al., 1987). 

TCDD given 2 days prior to or concurrently with methylcholanthrene did not affect methyl-cholanthrene-induced carcinogenicity in C57BL/6 mice (Kouri et al. 1978) in contrast, 2,3,7,8-TCDD pretreatment (intraperitoneal or subcutaneous) of DBA/2 mice slightly increased the carcinogenic index. 

Fig. 3. Effect of protein L injection on the proliferation capacity of splenocytes. Transgenic 5-feature mice [46] were injected intraperitoneally with 1 mg of recombinant protein L or the control protein HEL on days 1, 3, 5, 7 and 9. Spleen cells were washed and then cultured at a concentration of 2 X 105 cells in 100 pi in 96-well, round-bottom plates for 18 h in the presence of F(ab )2 anti-human IgM or lipopolysaccharide (LPS). Incorporation of 3H-thymidine was measured and proliferation indexes were calculated. White bars = Control, non-injected mice gray bars = mice injected with HEL black bars = mice injected with protein L. 

Regulatory FDA 21CFR 100.130, 101.9, 101.80, 175.300, 175.320, 177.1390, 177.2420, 180.25 GRAS Japan approved Europe listed UK approved FDA approved for parenterals, intramuscular injectables, intraperitoneal injectables, intrapleural injectables, intravenous, ophthalmics, orals USP, BP compliance Manuf./Distrib. AB R Lundberg ADA Int l. http //www.joinme.net/ada/index.htm, ADM http //www.admworid.com, AMRESCO http //www.amresco-inc.com, Aceto http //WWW. aceto. com Adept Sol ns. Aldrich http //www.sigma-aidrich.com, Alfa Aesar http //www.aifa.com, Alfa Chem... 

---