Imprinted polymers, preparation

Lubke C, Lubke M, Whitcombe MJ, Vulfson EN. Imprinted polymers prepared with stoichiometric template-monomer complexes efficient binding of ampiciUin from aqueous solutions. Macromolecules 2000 1433 5098-5105. 

Uezu K, Nakamura H, Kanno J, Sugo T, Goto M, Nakashio F. Metal ion-imprinted polymer prepared by the combination of surface template polymerization with postirradiation hy gamma-rays. Macromolecules 1997 30 3888-3891. 

Competitive MIP-ILAs are based on the first configuration the analyte competes with a labeled derivative for the specific binding sites of the imprinted polymer prepared in the form of beads or thin films. 

Cacho, C., E. Turiel, A. Martin-Esteban, C. Perez-Conde, and C. Camara (2004). Characterization and quality assessment of binding sites on a propazine-imprinted polymer prepared by precipitation polymerization. J. Chromatogr. B, 802 347-353. 

Southard GE, Van Houten KA, Ott EW Jr, Murray GM. Luminescent sensing of orga-nophosphates using europium(III) containing imprinted polymers prepared by RAFT polymerization. Anal Chim Acta 2007 581 202-7. 

Fig. 2.13. Separation factor (a) versus column temperature in the chromatographic resolution of D,L-PA on L-PA imprinted polymers prepared by thermochemical initiation at 60/ 90/120°C (24 h at each temperature) using acetonitrile as porogen and photochemical initiation at 15°C for 24 h using dichloromethane as porogen. For the thermochemically polymerised material the mobile phase was 5% acetic acid in acetonitrile and for the photochemically polymerised material the mobile phase was acetonitrile/water/acetic acid 92.5/2.5/5 (v/v/v). From Sellergren et al. [27] and Sellergren and Shea [13].

It is important to notice that the amidine moiety can act as a binding group and as a base at the same time. The importance of this dual nature will become apparent below, when we discuss the catalytic properties of imprinted polymers prepared using this functional group. 

CHROMATOGRAPHIC RETENTION OF TRIAZINES (10 NMOLE INJECTED SEPARATELY) ON AME IMPRINTED POLYMERS PREPARED AT DIFFERENT PRESSURES [110]... 

CAPACITY FACTORS OF 9EA IMPRINTED POLYMERS PREPARED AND EVALUATED USING ACETONITRILE OR CHLOROFORM AS DILUENT AND MOBILE PHASE... 

In situ molecular imprinting can be defined as a technique for preparing imprinted polymers in a place where the polymers are subsequently utilised. Imprinted polymers prepared by an in situ technique, therefore, require no subse-... 

Molecularly Imprinted Polymers -Preparation, Biomedical Applications and Technical Challenges... 

Rachkov, A., Hu, M., Bulgarevich, E., Matsumoto, T., and Minoura, N. (2004) Molecularly imprinted polymers prepared in aqueous solution selective for [Sar Ala8] angiotensin II. Analytica Chimica Acta, 504,191 197. 

Molecularly imprinted polymers -preparation, biomedical applications and technical challenges Allender, C. J. Brain, K. R. Heard, C. M. Prog. Med. Chem. 1999, 36, 235-291. 

Theophylline-imprinted polymers prepared with MAA and EDMA were utilized for SPR sensors, in which the particles were immobilized on the silver film on the SPR sensor chip by evaporation from acetonitrile-acetic acid (99 1 v/v) containing the particles [20]. The detection limit was reported to be 0.4 mg/mL of theophylline in aqueous solution. 

More recently, a diastereoselective molecularly imprinted fluorescent polymer for (-)-cinchonidine was prepared by the combined use of methacrylic acid and vinyl-substituted zinc(II) porphyrin monomer as functional monomers [24], Compared to the reference imprinted polymers using either MAA or zinc(II) porphyrin as a functional monomer, the imprinted polymer prepared with both MAA and the porphyrin... 

Torres, J. J., Gsponer, N., Ramirez, C. L., Vera, D. M., Montejano, H. A., Chesta, C. A. (2012). Experimental and theoretical studies on the enantioselectivity of molecularly imprinted polymers prepared with a chiral functional monomer. I Chromatoar. A. 1266,24-33. 

MIP2—an imprinted polymer prepared exactly the same way as the MIP, but against a compound (T2) that is structurally related to the template. 

Figure 8 (a) Binding of cholesterol to cholesterol-imprinted and control polymers, from a 2 mM solution of cholesterol in hexane, as a function of polymer concentration, (b) Binding of cholesterol and various cholesterol analogues (2 mM) to the cholesterol-imprinted polymer, prepared by the sacrificial spacer method. Reprinted with permission from Journal of the American Chemical Society. Copyright 1995 American Chemical Society (Ref. 10). 

One consequence of the uniform binding site distribution and high capacity of these polymers is that they may be rather better suited to the preparation of chromatographic (HPLC) stationary phases than noncovalently imprinted materials. In fact this was the conclusion arrived at by Hwang and Lee [15], who compared the chromatographic performance of cholesterol-imprinted polymers prepared by the semi-covalent (carbonate spacer) method with noncovalent MIPs incorporating... 

Flores, A. Cunliffe, D. Whitcombe, M.J. Vulfson, E.N. Imprinted polymers prepared by aqueous suspension polymerization. J. Appl. Polym. Sci. 2000, 77, 1841 1850. 

Hwang, C.C. Lee, W.C. Chromatographic characteristics of cholesterol-imprinted polymers prepared by covalent and non-covalent imprinting methods. J. Chromatogr. 

---