Hydroxylated polychlorinated biphenyls

Arcaro KF, Vakharia DD, Yang Y, et al. 1998. Lack of synergy by mixtures of weakly estrogenic hydroxylated polychlorinated biphenyls and pesticides. Environ Health Perspect 106(Suppl. 4) 1041-1046. 

Wiegel J, X Zhang, Q Wu (1999) Anaerobic dehalogenation of hydroxylated polychlorinated biphenyls by Desulfitobacterium dehalogenans. Appl Environ Microbiol 65 2217-2221. 

Satoh, A. Y. Trosko, ]. E. Masten, S. ]. Epigenetic Toxicity of Hydroxylated Biphenyls and Hydroxylated Polychlorinated Biphenyls on Normal Rat Liver Epithelial Cells. Environ. Sci. Technol. 2003, 37, 2727-2733. 

Gardner AM, Righter HF, Roach JAG. 1976. Excretion of hydroxylated polychlorinated biphenyl metabolites in cow s milk. J Assoc Off Anal Chem 59(2) 273-277. 

Moder, M., Zenkevich, I. G., Kollner, G., and Popp, P. New Approach in the precalculation of GC-Retention Indices of Hydroxylated Polychlorinated Biphenyls on HP-5 Liquid Phase , Proceedings of the 20th International Symposium on Chromatography, 25-29.05. 1998, Riva, A 15, in Fundamentals, CD produced by Naxos Software Soultions, Schriesheim, Germany. 

Buckman, A.H. Brown, S.B. Small, J. Muir, D.C.G. Parrott, J. Solomon, K.R. Fisk, A.T., Role of temperature and enzyme induction in the biotransformation of polychlorinated biphenyls and bioformation of hydroxylated polychlorinated biphenyls by rainbow trout Oncorhynchus mykiss). Environ Sci. Technol. 2007, 41, 3856-3863. 

Ueno, D. Darling, C. Alaee, M. Campbell, L. Pacepavicius, G. Teixeira, C. Muir, D. Detection of hydroxylated polychlorinated biphenyls (OH-PCBs) in the abiotic environment Surface water and precipitation from Ontario, Canada Environ. Sci. Technol. 2007, 41, 1841-1848. 

Methyl Sulfone and Hydroxylated Polychlorinated Biphenyls in Wildlife and Humans... 

Connor K, Ramamootrhy K, Moore M, et al. 1997. Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens Structure-activity relationships. Toxicol Appl Pharmacol 145 111-123. 

Kramer VJ, Helferich WG, Bergman A, et al. 1997. Hydroxylated polychlorinated biphenyl metabolites are anti-estrogenic in a stably transfected human breast adenocarcinoma (MCF7) cell line. Toxicol Appl Pharmacol 144 363-374. 

Moore M, Mustain M, Daniel K, et al. 1997. Antiestrogenic activity of hydroxylated polychlorinated biphenyl congeners identified in human serum. Toxicol Appl Pharmacol 142 160-168. 

Safe SH, Connor K, Raamamorthy K, et al. 1998. Estrogenic activity of hydroxylated polychlorinated biphenyls (PCBs) and their interactions. In Eisenbrand G, ed. Hormonally active agents in food Symposium. Weinheim, ERG Wiley-VCH, 200-207. 

Schuur AG, Bergman A, Brouwer A, et al. 1999. Effects of pentachlorophenol and hydroxylated polychlorinated biphenyls on thyroid hormone conjugation in a rat and a human hepatoma cell line. Toxicol in Vitro 13 417-425. 

One of the first SULTlAl inhibitors identified in the rat liver was 2, 6-dichloro-4-nitrophenol (DCNP) (Mulder and Scholtens, 1977). DCNP is a dead-end inhibitor, and exhibits low IC50 values toward SULTlAl and SULT 1 A3 (Seah and Wong, 1994). Hydroxylated polychlorinated biphenyls (HPCBs) are potent inhibitors of recombinant human SULTIEI. HPCBs exhibit low micromolar IC50 values toward thyroid hormones (Schuur et al., 1998). Several dietary chemicals such as quercetin, curcumin, and flavones are known to inhibit SULTs. Some commonly used drugs that inhibit SULTlAl and SULT1A3 activity include NSAIDs such as mefenamic acid, naproxen, and salicylic acid. 

Wagner-Dobler I, von Canstein H, Li Y, Timmis KN, Deckwer W-D (2000) Removal of mercury from chemical wastewater by microorganisms in technical scale. Environ Sci Technol 34 4628-4634 Wiegel J, Zhang X, Wu Q (1999) Anaerobic dehalogenation of hydroxylated polychlorinated biphenyls by Desulfitobacterium dehalogenans. Appl Environ Microbiol 65 2217—2221... 

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