Hydrogen peroxide sensor

HYDROGEN PEROXIDE SENSOR WITH ADVANCED ANALYTICAL PERFORMANCES... 

Lobnik A., Cajlakovic M., Sol-gel based optical sensor for continuous determination of dissolved hydrogen peroxide, Sensors Actuators B 2001 74 194-199. 

Preuschoff F., Spohn U., Blankenstein G., Mohr G., Kula M.R., Chemiluminometric hydrogen peroxide sensor for flow injection analysis, Fresenius J. Anal. Chem., 1993 346 924-929. 

E.A. Puganova and A.A. Karyakin, New materials based on nanostructured Prussian blue for development of hydrogen peroxide sensors. Sens. Actuators B chem. 109, 167-170 (2005). 

R. Garjonyte and A. Malinauskas, Operational stability of amperometric hydrogen peroxide sensors, based on ferrous and copper hexacyanoferrates. Sens. Actuators, B B56, 93—97 (1999). 

C.H. Lei and J.Q. Deng, Hydrogen peroxide sensor based on coimmobilized methylene green and horseradish peroxidase in the same montonorillonite-modified bovine serum albumin-glutaraldehyde matrix on a glassy carbon electrode surface. Anal. Chem. 68, 3344—3349 (1996). 

Y. Xiao, H.X. Ju, and H.Y. Chen, Hydrogen peroxide sensor based on horseradish peroxidase-labeled Au colloids immobilized on gold electrode surface by cysteamine monolayer. Anal. Chim. Acta. 391,... 

J.D. Zhang and M. Oyama, A hydrogen peroxide sensor based on the peroxidase activity of haemoglobin immobilized on gold nanoparticles-modified ITO electrode. Electrochim. Acta 50, 85-90 (2004). 

Wang, L., et al., A novel hydrogen peroxide sensor based on Ag nanoparticles etectrodeposited on chitosan-graphene oxide/cysteamine-modified gold electrode. Journal of Solid State Electrochemistry, 2012.16(4) p. 1693-1700. 

There are two major problems encountered with this approach. First is the selfinhibition caused by the hydrogen peroxide this has been mentioned before. It is less acute in this case than in the hydrogen peroxide sensor because the catalase substantially eliminates any excess of H2O2. The second problem is encountered when the electrode is used in vivo. The tissue or blood concentration of oxygen, which is the cosubstrate, is low and at high glucose concentrations the current becomes limited by the availability of oxygen. 

The aimed use of the FIA principle in the hydrogen peroxide sensor system is similar. More specifically, the aim of this part of the research was to verify whether the following approach could lead to the desired result. A constant flow of a bleaching solution (flow) is mixed with a constant flow of a solution with a known sodium hydroxide concentration (injection). This concentration depends on the final pH of the process solution to be established and is chosen in such a way that, after homogenising the two liquid... 

Scheme of the detection cell of the hydrogen peroxide sensor expanded with the FIA system. The inner chamber has a 20-cm length and a 1-cm diameter (1) working electrode, (2) reference electrode, (3) counter electrode, (4) combined glass electrode, and (5) temperature sensor, surface of the working electrode equals 7 mm2. 

Fig. 24.2. Operational stability of hydrogen peroxide sensors (PB-modified sensors). Applied potential —50mV vs. int. ref. Continuous monitoring of current in continuous flow mode (10 pi min-1). Arrows indicate where solution of hydrogen peroxide was renewed, (a) Two sensors tested with 10-4 and 2 x 10-4moll-1 of hydrogen peroxide, (b) Six months old sensor tested with a solution of 2 x 10-4moll-1 of hydrogen peroxide. Reprinted from Ref. [59] with permission from Elsevier.

A. Malinauskas, R. Araminaite, G. Mickeviciute and R. Garjonyte, Evaluation of operational stability of Prussian blue and cobalt hexacyanofer-rate-based amperometric hydrogen peroxide sensors for biosensing application, Mater. Sci. Eng. C, 24 (2004) 513-519. 

Preparation of Prussian blue-modified screen-printed electrodes via a chemical deposition for mass production of stable hydrogen peroxide sensors... 

The factors that affect the performance of H2O2 biosensor are (i) the type of enzyme, (ii) the immol sation method, and (iii) the thickness of the created enzyme layer. Immobilisation processes are quite an important Eictor for the development of biosensors. This step has been smdied extensively, in order to achieve easy operation, quick measurement and reduce the cost of the analysis. The methods of enzymes immobilisation used for the development of hydrogen peroxide sensors can be divided into five major groups (Fig. 3) ... 

Karyakin and Karyakina have developed a hydrogen peroxide sensor, based on Prussian Blue deposited on glassy carbon electrodes. Prussian Blue was considered an artificial peroxidase due to its high catalytic activity and selectivity, which could be compared with biocatalysis. The application of Prussian Blue modified electrodes enabled the sensing of H2O2 at around 0 V vs. SCE. The electrocatalytic reduction of H2O2 in the presence of O2 was found to be better for Prussian Blue deposited on glassy carbon electrodes than for platinum covered electrodes. Furthermore, these electrodes were more stable and active and less expensive than the platinum and peroxidase modified electrodes. The response was linear up to 0.1-100 pM and the detection limit found to be 10 M. 

Qian J, Liu Y, Liu H et al. Characterization of regenerated silk fibroin membrane for immobilisation of peroxidase and construction of an amperometric hydrogen peroxide sensor employing phenazine methosulphate as electron shuttle. J Electroanal Chem 1995 397 157-162. 

T. Zhang, R. Yuan, Y. Chai, W. Li, and S. Ling, A novel nonenz3fmatic hydrogen peroxide sensor based on a polypyrrole nanowire-copper nanocomposite modified gold electrode, Sensors, 8, 5141-5152 (2008). 

Wang, Q., Yun, Y., and Zheng, J. (2009). Nonenqmiatic hydrogen peroxide sensor based on a polyaniline-single walled carbon nanotubes composite in a room temperature ionic liquid, Microchim. Acta, 167, pp. 153-157. 

Cui H, Wang W, Duan C-F, Dong Y-P, Guo J-Z (2007) Synthesis, characterization, and electrochemiluminescence of luminol-reduced gold nanoparticles and their application in a hydrogen peroxide sensor. Chem Eur J 13(24) 6975-6984. doi 10.1002/chem.200700011... 

Li, G., Wang, Y, and Xu, H. (2007) A hydrogen peroxide sensor prepared by electro-polymerization of pyrrole based on screen-printed carbon paste electrodes. Sensors, 7, 239- 250. 

Xiao F, Zhao F, Zhang Y, Guo G, Ztaig B (2009) Ultrasmiic electrodeposition of gold-platinum alloy nanoparticles on ionic liqnid-chitosan cmnposite film and their applicatimi in fabricating nonenzyme hydrogen peroxide sensors. J Phys Chcm C 113 849-855... 

Luo F, Yin J, Gao F, Wang L (2009) A non-enzyme hydrogen peroxide sensor based on core/ shell silica nanoparticles using synchronous fluorescence spectroscopy. Microchim Acta 165 23-28... 

First generation oxygen and hydrogen peroxide sensor-based systems... 

Mizutani F, Ohta E, Mie Y, Niwa O, Yasukawa T (2008) Enzyme immunoassay of insulin at picomolar levels based on the coulometric determinatimi of hydrogen peroxide. Sensors Actuat B Chem 135(l) 304-308... 

---