Advanced sensor for hydrogen peroxide

An advanced sensor for hydrogen peroxide based on Prussian blue... 

Amperometric sensors for electroactive compounds Advanced sensor for hydrogen peroxide... 

We report here the results obtained by the use of a screen-printed electrode as electrochemical probe to be coupled with a microdialysis fibre for continuous glucose monitoring. The most significant advance is represented by the introduction of a mediator (PB) as the principal factor for hydrogen peroxide measurement. The improved operational stability observed with the PB-modified screen-printed electrodes has demonstrated that these sensors could serve as tool to be applied for the continuous monitoring of many analytes. The application to diabetic care seems to be the most promising and advantageous area in which to test these sensors. 

Since hydrogen peroxide is the product of reactions catalysed by a huge number of oxidase enzymes and is essential in food, pharmaceutical, and envitonmental analysis, its detection was and remains a necessity. Many attempts have been made in order to develop a biosensor that would be sensitive, stable, inexpensive and easy to handle. The most popular and efficient of them are amperometric enzyme biosensors, which utihsed different types of mediators and enzymes, mosdy peroxidase and catalase. Unfortunately many of the sensors developed do not mea the requirements for a practical device, which has a balance of technological charaaeristics (sensitivity, reliability, stability) and commercial adaptability (easy of mass production and low price). Thus a window of opportunity still remains open for future development. We hope that the present work will inspire other researches for further advances in the area of biosensors, in particular sensors for detection of such an important analyte as hydrogen peroxide. 

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