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Biodegradation control

Figure 23. Scheme of biodegradeable controlled release approaches. [Pg.178]

Thoma, K. Alex, R. Fensch-Kleemann, E. Biodegradable controlled release implants based on (3-tricalcium phosphate ceramic. I. Preparation and characterization of porous (3-tricalcium phosphate ceramic pellets. Eur. J. Pharm. Biopharm. 1992, 38, 101-106. [Pg.3256]

Peri D, Bogdansky S, Allababidi S, Shah JC. Development of an implantable, biodegradable, controlled drug delivery system for local antibiotic therapy. Drug Dev Ind Pharm 1994 20 1341-1352. [Pg.310]

Brem, H. Kader, A. Epstein, J.I. Tamargo, R.J. Domb, A. Langer, R. Leong, K.W. Biocompatibility of a biodegradable, controlled-release polymer in the rabbit brain. Selec. Cancer Ther. 1989, 5 (2), 55-65. [Pg.2256]

Figure 2 (a) Bulk erosion of biodegradable controlled-release polymer implants leads to unpredictable release profiles, (b) Polymers exhibiting surface erosion release drug at nearly constant rate (zero-order kinetics) as they dissolve in water. (From Ref. 61.)... [Pg.330]

Tamargo RJ, Epstein JI, Reinhard CS, Chasin M, Brem H. Brain biocompatibility of a biodegradable, controlled-release polymer in rats. J Biomed Mater Res 1989 23 253—266. [Pg.370]

Gursel, I. Korkusuz, F. Turesin, E Alaeddinoglu, N. G. and Hasirci, V In vivo application of biodegradable controlled antibiotic release systems for the treatment of implant-related osteomyelitis. Biomaterials, 2001, 22(1), 73-80. [Pg.45]

Korkusuz, R Korkusuz, P Eksioglu, R Gursel, L and Hasirci, V In vivo response to biodegradable controlled antibiotic release systems. J. Biomed. Mater. Res. 2001, 55(2), 217-228. [Pg.45]

H.K. Makadia, S.J. Siegel, Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery carrier. Polymers 3 (3) (2011) 1377-1397. [Pg.348]

Desirable at this point would be an implantable naltrexone delivery system that would not depend on patient compliance. It could be a biodegradable controlled release device, for example, injectable by hypodermic syringe for relatively short-term release. Alternatively, it could be implanted by trocar or by laparoscope for release for months as a biocompatible and biodegradable yet removable vehicle should patients circumstances warrant substantial pain control. As demonstrated below (see Figure 9.39), properly designed protein-based materials exhibit this potential. [Pg.466]

Sendil D, Wise DL, Hasirci V (2002) Assessment of biodegradable controlled release rod systems for pain relief applications. J Biomater Sci 13 1-15... [Pg.448]

Nowadays, PS/PLA blends with a cocontinuous structure are one of the most attractive blends for generating biodegradable controlled release devices and tissue engineering scaffolds, since after selective removal of the PS phase from the blends, highly structured and completely interconnected porous PLA structures are obtained [32, 39-41]. The pore... [Pg.230]

S.R. Jameela, T.V. Kumary, A.V. Lai, and A. Jayakrishnan, Progesterone-loaded chitosan microspheres A long acting biodegradable controlled delivery system, J. Control Release, 52, 17-24, 1998. [Pg.31]

Jameela SR, Kumary TV, Lai AV et al (1998) Progesterone-loaded chitosan microspheres a long acting biodegradable controlled deUvery system. J Control Release 52 17-24... [Pg.225]

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See also in sourсe #XX -- [ Pg.106 ]



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