Hydrocortisone solution, alcoholic

Admixture incompatibilities - Magnesium sulfate in solution may result in a precipitate formation when mixed with solutions containing Alcohol (in high concentrations) alkali carbonates and bicarbonates alkali hydroxides arsenates barium calcium clindamycin phosphate heavy metals hydrocortisone sodium succinate phosphates polymyxin B sulfate procaine hydrochloride salicylates strontium tartrates. [Pg.24]

Prochlorperazine Edisylate Prochlorperazine edisylate is not compatible with sodium chloride solutions containing methyl hydroxybenzoate and propyl hydroxy-benzoate as preservatives, but is compatible with solutions containing benzyl alcohol. Prochlorperazine edisylate salts are incompatible with a number of drugs such as aminophylline, amphotericin, ampicillin sodium, some barbiturates, ben-zylpenicillin salts, calcium gluconate, cefmetazole sodium, cephalothin sodium, chloramphenicol sodium succinate, chlorothiazide sodium, chloramphenicol, morphine sulfate containing phenol, magnesium trisilicate mixture, sodium succinate, chlorothiazide sodium, dimenhydrinate, heparin sodium, hydrocortisone sodium succinate, midazolam hydrochloride, and some sulfonamides.166... [Pg.355]

Carboxylic half-esters (e.g. hemisuccinates) of phenols are easily hydrolyzed in aqueous solution and are therefore not recommended for the solubilization of phenolic compounds. Even hemisuccinates of alcohols suffer somewhat from stability problems and must be supplied as lyophi-lized (freeze-dried) powders for reconstitution in water and used within 48 h (see, for example, the monographies chloramphenicol sodium succinate or hydrocortisone sodium succinate in The Handbook on Injectable Drugs,see also Anderson et... [Pg.770]

Derendorf, H. Rohdewald, R Hochhaus, G. Moellmann, H. HPLC determination of glucocorticoid alcohols, their phosphates and hydrocortisone in aqueous solutions and biologiceil fluids. J.Pharm.Biomed.Anal., 1986, 4, 197-206... [Pg.739]

Rego, A. Nelson, B. Simultaneous determination of hydrocortisone and benzyl alcohol in pharmaceutical formulations by reversed-phase high-pressure liquid chromatography. J.Pharm.Sci., 1982, 71, 1219-1223 [simultaneous benzaldehyde, benzoic acid, benzyl alcohol phenethyl alcohol (IS) creams gels ointments solutions]... [Pg.740]