Human umbilical cord endothelial cells

Nieda M, Nicol A, Denning-Kendall P, Sweetenham J, Bradley B, Hows J. Endothelial cell precursors are normal components of human umbilical cord blood. Br J Haematol 1997 98 775-777. 

HUVECs human umbilical cord vein endothelial cells... 

IL-8 also acts on nonleukocytic cells such as melanoma cells and synovial fibroblasts (16) in vitro. IL-8 enhances viral replication, particularly cytomegalovirus, in human fibroblasts in vitro (7 7). IL-8 significantly inhibits the antiviral activities of interferon-a (18). IL-8 also increases the adhesion to unstimulated human umbilical cord vein endothelial cells (HU VECs) (19), enhances transendothelial migration (20), and induces angiogenesis in rat cornea (21). 

Standards prostaglandins, prostacyclin and thromboxane Ba were generous gifts from Dr J.E. Pike of Upjohn, Kalamazoo. Endothelial cell micro-somes used to inhibit platelet aggregation were obtained from human umbilical cord and their inhibiting activity was completely abolished by 15-hydroperoxy arachidonic acid or tranylcypromine. 

HUVECs Human endothelial cells isolated from umbilical cord... 

Human endothelial cells isolated from umbilical cord (HUVECs) were seeded on pure and RGD modified gels to determine the cell-adhesive characteristics of the compared materials. Cell adhesion and proliferation (or apoptosis) were observed by means of microscopic and colorimetric techniques. 

Fig. 9 Viability of human endothelial cells isolated from umbilical cord on RGD modified gels (here shown for Type B) monitored by the live/dead assay. Representative pictures shows live (fluorescein di-O-acetate, viable cells visible as light spots, left) and dead (propidium iodide, no dead cells visible, right) staining. Image after 1 day culture. Scale bar 200 pm...

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