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Human pluripotent stem cell reprogramming

Zhang J et al (2009) Functional cardiomyo-cytes derived from human induced pluripotent stem cells. Circ Res 104(4) e30-e41 Zwi L et al (2009) Cardiomyocyte differentiation of human induced pluripotent stem cells. Circulation 120(15) 1513-1523 Burridge PW et al (2012) Production of de novo cardiomyocytes human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell 10(l) 16-28 Rattman SJ et al (2011) Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and... [Pg.349]

Fig. 4 Using Human Pluripotent Stem Cells for Disease Modeling. Patient-specific somatic cells (e.g. skin fibroblasts) can be reprogrammed into induced pluripotent stem cells (iPSCs) using specific genetic factors. Neuronal cells with specific disease phenotypes can be differentiated to neural stem cells. The development of in vitro cellular models based on patient-specific cells may lead to personalized medicine approaches with minimal side effects and improved pharmacological efficacy. Fig. 4 Using Human Pluripotent Stem Cells for Disease Modeling. Patient-specific somatic cells (e.g. skin fibroblasts) can be reprogrammed into induced pluripotent stem cells (iPSCs) using specific genetic factors. Neuronal cells with specific disease phenotypes can be differentiated to neural stem cells. The development of in vitro cellular models based on patient-specific cells may lead to personalized medicine approaches with minimal side effects and improved pharmacological efficacy.
P. W. Burridge, G. Keller, J. D. Gold, J. C. Wu, Production of de novo cardiomyocytes human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell 10, 16-28 (2012). [Pg.360]

Zhou, W. Freed, C. R. 2009. Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem Cells, 27, 2667-74. [Pg.345]

K. Si-Tayeb, F. K. Noto, A. Sepac, F. Sedlic, Z. J. Bosnjak, J. W. Lough, S. A. Duncan, Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors. BMC Dev Biol 10, 81 (2010). [Pg.363]

Kim D, Kim CH, Moon II et al (2009) Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4 472-476... [Pg.83]

Nagata, S., Toyoda, M., Yamaguchi, S. et al. 2009. Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells. Genes Cells 14 1395-404. [Pg.755]

Rodriguez-Piza, L, Richaud-Patin, Y, Vassena, R. et al. 2010. Reprogramming of human fibroblasts to induced pluripotent stem cells under xeno-free conditions. Stem Cells 28 36-44. [Pg.755]

Warren L et al (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7(5) 618-630... [Pg.349]

Anokye-Danso F et al (2011) Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8(4) 376-388... [Pg.349]

Another quantum leap for modern biotechnology was the first cloned mammal by Ian Willmut in 1996 (see his quote for Modern Biopharmaceuticals ) by means of somatic cell nuclear transfer (SCNT) -the sheep Dolly . Then, in 2004, the first human embryo was cloned by a team led by Woo Suk Hwang, who was able to obtain pluripotent embryonic stem cells by SCNT of reprogrammed human adult cells. The highly differentiated genetic pro-... [Pg.1957]

F. Anokye-Danso, C. M. Trivedi, D. Juhr, M. Gupta, Z. Cui, Y. Tian, Y. Zhang, W. Yang, P. J. Gruber, J. A. Epstein, Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8, 376-388 (2011). [Pg.360]

N. Miyoshi, H. Ishii, H. Nagano, N. Haraguchi, D. L. Dewi, Y. Kano, S. Nishikawa, M. Tanemura, K. Mimori, F. Tanaka, Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell 8,633-638 (2011). [Pg.362]

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See also in sourсe #XX -- [ Pg.347 ]



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