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Horses anthelmintics

Nitriles react with ammonia, or primary or secondary amines in the presence of an acid catalyst to give amidines (Scheme 26) (75, 77, 81). The catalysts used are hydrochloric acid and aluminium chloride. The amidines are anthelmintics for animals such as sheep, goats, cattle, horses, and Swine. [Pg.532]

Levamisole. The racemic mixture of the d and / isomers of tetramisole [6649-23-6] was first described in 1966. It is used as an anthelmintic against a wide variety of nematodes, including lungworms, of mminants, swine, horses, dogs, and poultry. Anthelmintic activity resides in the /-isomer, levamisole [14769-73-4], the form used. [Pg.404]

Carbon disulfide (qv) is used, in combination with other orally administered anthelmintics, by stomach tube for hots Gastrophilus sp. larvae) and ascarids (roundworms) of horses. [Pg.404]

The microorganism was classified as a new species of actinomycete. Streptomyces avermitilis. Its anthelmintic activity was shown to reside in 8 closely related macrocyclic lactones, named avermectins, which were also found to possess activity against free-living and parasitic arthropods. One of the natural components, avermectin is now being evaluated as a pesticide for the control of mites of citrus and cotton crops and control of the Red Imported Fire Ant. A chemical derivative, 22,23-dihydroavermectin or ivermectin, has been developed as an antiparasitic agent. It is being marketed for use in cattle, horses and sheep and is expected to become available for swine and dogs. [Pg.5]

Equine anthelmintic, for the prevention of strongylus vulgaris larval infestation in horses Strongid C Pyrantel tartrate Dehydrated Alfalfa meal, wheat middlings, cane molasses, mineral oil... [Pg.222]

Thiabendazole, pjrantel taitoate, and phenothi-azine are the commonest anthelmintics found in horses. [Pg.99]

DiPietro J A, Todd K S. Lock T F et al 1982 Anthelmintic efficacy of ivermectin given intramuscularly in horses. American Journal of Veterinary Research 43 145-148 DiPietro J A, Hutchens D E, Lock T F et al 1997 Clinical trial of moxidectin oral gel in horses. Veterinary Parasitology 72(2) 167-177... [Pg.73]

French D D, Kiel T M, Foil C S et al 1988 Efficacy of ivermectin in paste and injectable formulations against microfilariae of Onchocerca cervicalis and resolution of associated dermatitis in horses. American Journal of Veterinary Research 49 1550-1554 Harnett W 1998 The anthelmintic action of praziquantel. [Pg.73]

Lloyd S, Smith J, Connan R M et al 2000 Parasite control methods used by horse owners factors predisposing to the development of anthelmintic resistance in nemotodes. Veterinary Record 146 487-492 Love S, Murphy D, Mellor D 1999 Pathogenicity of cyathostome infection. Veterinary Parasitology 85 113-122... [Pg.74]

Sangster N C 1999 Pharmacology of anthelmintic resistance in cyathostomes will it occur with the avermectin millbemycins. Veterinary Parasitology 85 189-204 Tarigo-Martinie J L, Wyatt A R, Kaplan R M 2001 Prevalence and clinical implications of anthelmintic resistance In cyathostomes in horses. Journal of the American Veterinary Medical Association 218 1957-1960 Taylor S M, Kenny J 1995 Comparison of moxidectin with ivermectin and pyrantel embonate for reduction of faecal egg count in horses. Veterinary Record 137 516-518 Uhlinger C 1990 Effects of three anthelmintic schedules on the incidence of coiic in horses. Equine Veterinary Journal 22 251-254... [Pg.74]

The broad-spectrum anthelmintic nitazoxanide has been undergoing efficacy trials in the USA for the treatment of EPM (Vatistas et al 1999). This drug is currently used to combat intestinal parasites of humans in developing countries and in patients with the acquired immimodeficiency syndrome complicated by secondary protozoal infections. Nitazoxanide is administered daily for 28 days as an oral paste. The side-effects of this drug are more serious than with other medications because it kills other parasites in addition to S. neurona. This has led to recommendations for deworming with another anthelmintic prior to starting this treatment (McClure Palma 1999). Nitazoxanide may also cause colic in treated horses. [Pg.147]

When absorption takes place rapidly, which is usual for conventional dosage forms, fca > kd, but when absorption takes place slowly and ka < k(j the flip-flop phenomenon occurs, whereby the rate of absorption controls the rate of elimination of the drug. This situation applies not only to sustained-release oral dosage forms administered to dogs, but also to phenylbutazone and meclofe-namic acid in horses, salicylate administered as an aspirin bolus to cattle and oral suspensions of benzimidazole anthelmintics in ruminant species. [Pg.58]

Cawthorne, R.J.G., Anthelmintics for Cattle, Sheep, Goats, Pigs, Horses and Poultry, Ministry of Agriculture, Fisheries and Food, Central Veterinary Laboraotory, New Haw Weybridge, Surrey, England (1984) cited in ref. 44. [Pg.193]

The benzimidazole anthelmintics have been extensively used to eradicate roundworms (nematodes) parasitizing the gastrointestinal tract, lungs, blood circulation, lymphatic system, body cavity, heart and subcutaneous tissues of cattle, sheep, goats, horses, pigs, cats, dogs and poultry [14,173-176]. The important drugs which have been used to treat domestic animals, are summarised below ... [Pg.215]


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See also in sourсe #XX -- [ Pg.162 ]




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