Hormone clinical disorders

Hypopituitarism A clinical disorder characterized by complete or partial deficiency in pituitary hormone production. 

Singh MM (2001) Centchroman, a selective estrogen receptor modulator, as a contraceptive and for the management of hormone-related clinical disorders. Med Res Rev 21 302-347... 

The key feature of this two-step method is that the labeled hormone is physically prevented from interacting with serum binding proteins. This ensures that antibody binding of tracer is governed solely by the free hormone concentration and not by changes in thyroid hormone-binding proteins. Test results obtained with two-step methods correlate well with those obtained by reference methods across a wide range of clinical disorders. 

Clinical disorders of the thyroid can result from excessive or deficient production of thyroid hormone or from disorders of thyroid growth. 

Myxedema. Hypothyroidism (subnormal secretion of thyroid hormones), which is acquired anytime after birth, can develop into the severe clinical disorder of myxedema (named after the fluid accumulation appearing in the face and other areas of the body). Most cases of this disorder are found in females between ages 40 and 60. However, occasionally it is found in young children. Although there seems... 

The potent antidiuretic hormone AVP orchestrates the regulation of free water absorption, body fluid osmolality, cell contraction, blood volume, and blood pressure through stimulation of three G-protein-coupled receptor subtypes Vi-vascular types a and b, V2-renal, and V3-pituitary. Increased AVP secretion is the trademark of several pathophysiological disorders, including heart failure, impaired renal function, liver cirrhosis, and SIADH. As a consequence, these patients experience excess water retention or inadequate free-water excretion, which results in the dilution of sodium concentrations, frequently manifesting as clinical hyponatremia (serum sodium concentration <135mmol/L). This electrolyte imbalance increases mortality rates by 60-fold. Selective antagonism of the AVP V2 receptor promotes water... 

Thyroid disorders encompass a variety of disease states affecting thyroid hormone production or secretion that result in alterations in metabolic stability. Hyperthyroidism and hypothyroidism are the clinical and biochemical syndromes resulting from increased and decreased thyroid hormone production, respectively. 

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