Hormonal therapy estrogen-based

With estrogen-based therapy, there should be yearly breast exams, monthly breast self-examinations, and periodic mammograms. Women on hormonal therapy should undergo annual monitoring, including pelvic examination, blood pressure checks, and routine endometrial cancer surveillance. 

Estrogen-based postmenopausal hormone therapy should be used for the treatment of menopausal symptoms (i.e., vasomotor and urogenital symptoms) and, when specifically indicated, for osteoporosis prevention. 

Osteoporosis prevention remains an approved indication for estrogen-based hormone therapy, but alternative strategies are available and should be considered as first-line agents for asymptomatic women. Vitamin D deficiency should be excluded before any other treatment is prescribed... 

Isoflavones may be found in small amounts in soy-based infant formulas [10]. Isoflavones are found in whole soybeans and products including tofu, tempeh, and soy milk. Isoflavones are classified as both phytoestrogens (plant estrogens) and selective estrogen receptor modnlators. The phytoestrogenic effects of isoflavones have led to the use of soy foods and isoflavone supplements as alternatives to conventional hormone therapy. However, studies have found no long-term complications associated with isoflavones in infants fed soy-based formulas [10,17]. 

FIGURE 4—7 Effect of genotype on response to estrogen hormone replacement therapy. Depicted are pretreatment (base line) and posttreatment (follow-up) high-density lipoprotein (HDL) cholesterol levels in women of the C/C vs. C/T or T/T HMG-Co A reductase genotype... 

The search for phytoestrogens to use as a natural source of estrogen for hormone replacement therapy has been ongoing for many years. The interest in this topic is based... 

Koomen ER, Joosse A, Herings RMC, Casparie MK, Guchelaar HJ, Nijsten T. Estrogens, oral contraceptives and hormonal replacement therapy increase the incidence of cutaneous melanoma a population-based case-control study. Arm Oncol 2009 20 358-64. 

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