Hormonal NSAIDs

In summary, the true association between most dietary factors and the risk of colon cancer is unclear. The protective effects of fiber, calcium, and a diet low in fat are not completely known. Lifestyle factors such as NSAID use and hormone use appear to decrease the risk of colorectal cancer, whereas physical inactivity, alcohol use, and smoking appear to increase the risk of colon cancer. Clinical risk factors and genetic mutations are well-known risks for colon cancer. 

Considering all aspects, sex hormones, antibacterials, and antineoplastic agents were identified by Christensen as the three most relevant groups of chemicals concerning their potential human risk as a consequence of drug exposure via the environment [10]. Immunochemical methods for hormones and antibiotics have already been discussed above. In this section we will describe methods based on the use of antibodies for the analysis of analgesics, NSAIDs, and cytostatic agents. 

These NSAID MPC-7869 (R)-flurbiprofen) is a drug candidate (Phase III) for Alzheimer disease. It affects jS-amyloid deposition and metabolism and prevents cognitive deficits in transgenic animals. It is also being evaluated in hormone-naive prostate cancer (cf. infra). ... 

Treatments for autoimmune disease have traditionally been immunosuppressive, antiinflammatory or palliative. Non-immunological therapies, such as hormone replacement in Hashimoto s thyroiditis, treat the outcomes of the autoaggressive response. Dietary manipulation limits the severity of coeliac disease. Steroidal or NSAID treatment limits the inflammatory symptoms of many diseases. 

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