Hoffmann-LaRoche, Inc

The amount of Hquid crystals produced each year for appHcations is several tens of tons, with the vast majority designed specifically for display appHcations. Several of the largest producers of commercial Hquid crystals are E. Merck, Hoffmann-LaRoche Inc., and Chisso. E. M. Chemicals (Hawthorne, New York) is the distributor for E. Merck in the United States and Chisso America Inc. has an office in New York. Hoffmann-LaRoche and Di Nippon Inc. have joined forces to form a new company, Rodic. 

Because feed comprises over 80% of the cost of producing and fattening cattle, the maximum utilization of ever increasingly expensive rations is of upmost importance (179). Monensin under the trade name of Rumen sin (Elanco Products) was introduced in 1976 at a recommended level of 30 ppm in cattle feed. Lasalocid having the trade name Bovatec (Hoffmann-LaRoche, Inc.) was marketed some years later. 

The research described is supported in part by U S Public Health Service grants CA-12376 and CA-29602 from the National Cancer Institute, and by a gift from Hoffmann-LaRoche, Inc ... 

R. D. Daley, Ayerst Laboratories, Rouses Point, New York E. Debesis, Hoffmann-LaRoche, Inc., Nutley, New Jersey... 

Cell Culture. Human neuroblastoma IMR-32 (passaged through nude mice the cells were donated by Dr. Steven E. Brooks, Kingsbrook Jewish Medical Center, Brooklyn) and mouse neuroblastoma clones NIE-115, NS-20, and N-18) (donated by Dr. Shraga Makover, Hoffmann LaRoche, Inc., Nutley, New Jersey) were maintained in our laboratory as described previously (30,31). Confluent monolayers (6 to 8 x 10 cells per 250-ml Falcon plastic flask) were harvested for enzymatic studies with phosphate-buffered saline [7.0 mM potassium phosphate/0.14 M NaCl - buffer, pH 7.2 (Pi/NaCl)] containing 0.1% EDTA. 

Schlapfer, R. and Spiegelberg, H. US Patent 3,115,502 December 24, 1963 assigned to Hoffmann-LaRoche Inc. 

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