Hoechst Company

There have been many commercial and laboratory publications on the synthesis of ibuprofen. Two of the most popular ways to obtain ibuprofen are the Boots process and the Hoechst process. The Boots process is an older commercial process developed by the Boots Pure Dmg Company, the discoverers of ibuprofen in the 1960s, and the Hoechst process is a newer process developed by the Hoechst Company. Most of these routes to Ibuprofen begin with isobutylbenzene and use Friedel-Crafts acylation. The Boots process requires six steps, while the Hoechst process, with the assistance of catalysts, is completed in only three steps (Figure 20.2). 

ThelG Farben Company was formed in 1925 by the merging of Bayer with the BASF and Hoechst companies. Research initially focused on the polymerization of butadiene, a compound for which an economic synthesis had recently been discovered. 

An environmental load factor may be negative, which means that the weight of product formed exceeds the weight of materials wasted. An example comes from the Hoechst company in Germany, of which the fipco... 

Figure 7.9 A tube bundle crystallization plant of the Hoechst Company. (Reproduced with permission from Rittner and Steiner 1985.)...

From the bridged metallocene complexes, the bis-(indenyl) derivatives must be considered as the pioneer compounds to produce isotactic polypropylene. At the former Hoechst company, this system was optimized and commercialized for high activity of the catalyst and high molecular weight (ca. 1 000 000 g/mol) and high isospecifity (98%) of the polymer. ... 

So, too, the dyestuff maker, Farbwerke vorm. Meister Lucius Briining (Hoechst) found in America a loyal agent, who in time became very much part of the Hoechst "family." At first, Hoechst used independent agents, one of which had in 1882 employed the 15-year old American-born Herman Metz. From the 1880s until his death in 1934, Metz was associated with Hoechst and then LG. Farben—a half century relationship. And with Hoechst, as with Bayer and Badische, there was the same pattern, first Hoechst used independent agents and then owned sales outlets. Metz s letterhead in 1914 showed him to be president of Farbwerke Hoechst Company, New York, with branches in Boston, Philadelphia, Providence, Chicago, Charlotte, Atlanta, San Francisco, and Newark. In Newark, Hoechst had a small factory, that represented roughly 2 to 3 percent of U.S. dyestuff production. ... 

Two main methods of approach have been used firstly, an increase in the linearity of the alkyl chain used in alkyl benzene sulfonates, and secondly, the production of sodium alkane sulfonates by sulfoxidation of straight chain hydrocarbons in the Ci3"Ci7 band. The first process need not concern us here, but it would represent a serious competitor to any radiation-induced process. A considerable amount of work has been done on the y-ray-initiated sulfoxidation of hydrocarbons by the Esso Research Company in the United States aimed directly at the production of soft detergents. Latterly, work has also been carried out by the Hoechst Company in Germany. 

Researchers of the Hoechst company later optimized the structure of ansa zirconocene complexes by using different bridges and substituents at the indenyl rings, such as [Me2Si(2Me-4PhInd)2]ZrCl2 or [(CH3)2Si(2-CH3-4-Naph-Ind)2] ZrCl2 (structure shown in Fig. 6) [84]. They were able to obtain iPP with an activity of... 

Many companies, such as Standard Oil Company, Mitsubishi Chemical Corporation, BP Chemicals, Celanese, Hoechst Company, and Saudi Basic Industries Corp., have reported catalysts and processes. In 2000, SABIC developed a new process for acetic acid production through ethane oxidation (the Sabox process), and the construction of a 30,000 ton/year plant to produce acetic acid by ethane oxidation at Yanbu has been announced. ... 

For use as a softener in finishing Uquors, Hoechst Company markets a special formulation of a high molecular weight PEG under the trade name Finishing Wax WL. 

Hoechst Company Archives UA BASF D 03.4/1 Kuko Wissenschaftliche Referate Bitterfeld, Diineberg, Eilenbmg etc, 2. Sitzung, Referat Dr. Klatte-Rheinfelden, liber Vinylchlorid, no date, 1 and 6. 

Hoechst Company Archives (1966) Griindung der wissenschaftlichen Kunststojfkommission (Kuko) im Jahre 1930, Dokumente aus Hoechst-Archiven Beitrage zru- Geschichte der Chemie 16, n.p. 

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