Metz, Herman

Metz, C. E., Herman, B. A. Roe, C. A. (1998a). Statistical comparison of two ROC-curve estimates obtained from partially-paired datasets. Med Decis Making 18,110-21. 

Metz, C. E Herman, B. A. Shen, J. H. (1998b). Maximum likelihood estimation of receiver operating characteristic (ROC) curves from continuously-distributed data. Stat Med 17, 1033-53. 

Wallace KB, Hausner E, Herman E, Holt GD, MacGregor JT, Metz AL, Murphy E, Rosenblum IY, Sistare FD, York MJ. Seram troponins as biomarkers of drug-induced cardiac toxicity. Toxicol Pathol 2004 32(1) 106-21. 

So, too, the dyestuff maker, Farbwerke vorm. Meister Lucius Briining (Hoechst) found in America a loyal agent, who in time became very much part of the Hoechst "family." At first, Hoechst used independent agents, one of which had in 1882 employed the 15-year old American-born Herman Metz. From the 1880s until his death in 1934, Metz was associated with Hoechst and then LG. Farben—a half century relationship. And with Hoechst, as with Bayer and Badische, there was the same pattern, first Hoechst used independent agents and then owned sales outlets. Metz s letterhead in 1914 showed him to be president of Farbwerke Hoechst Company, New York, with branches in Boston, Philadelphia, Providence, Chicago, Charlotte, Atlanta, San Francisco, and Newark. In Newark, Hoechst had a small factory, that represented roughly 2 to 3 percent of U.S. dyestuff production. ... 

Herman Metz to the Medical Profession, Mar 1917, in file of Dermatological research laboratory at College of Physicians, Philadelphia, Historical Collection. I am indebted to Jonathan Liebenau for sending me a copy of this letter. Liebenau has been extremely helpful to me on this. 

Maffei HV, Metz G, Bampoe V, Shiner M, Herman S, Brook CG. 1977. Lactose intolerance, detected by the hydrogen breath test, in infants and children with chronic diarrhoea. Arch Dis Child 52 766-767. 

Herman Metz, the Hoechst importer, used his political connections from years in New York City government (1906-1910) and in Congress (1913-1915) to push officials in the Departments of Commerce and State to facilitate the diplomacy necessary to trade through the Atlantic war zone. While Metz was in Germany in late 1914 to extract a shipment, he grasped immediately... 

The first of the provisions that directly involved synthetic organic chemicals, Section 10 of TWEA, addressed patents and evolved directly out of controversy over Salvarsan, one of the most important synthetic organic pharmaceuticals. Herman Metz controlled Hoechst s intellectual property in the United States, including Paul Ehrlich s famous... 

The list of witnesses in the various hearings included many of the usual suspects Francis Garvan, Charles Herty, Herman Metz, but also Irenee du Pont, the president of Du Pont,... 

Like some textile industrialists, many importers and dealers of dyes opposed the tariff bills because it ran counter to their own economic interests. Of the importing agencies for the six major German dyes companies, only Kuttroff, Pickhardt Company and Herman Metz remained in business, and Metz had become primarily a manufacturer rather than an importer immediately after the war. The importers of dyes from countries other than Germany presented the importers case, although Metz and Paul Pickhardt were also prominent witnesses. Metz, in fact, earned the committees respect as one of the most knowledgeable witnesses in technical and sales... 

Another important witness for the government was Herman Metz. The government attorneys believed that the patents for Salvarsan and Neosalvarsan were among the most valuable purchased by the Chemical Foundation and that Metz, as the prewar supplier of Hoechst s anti syphilitic drugs, would be in the best position to testify to their worth. Under his FTC licenses on Salvarsan and Neosalvarsan, Metz paid 140,000 to the Treasury from 1919 to 1922. On the two products in 1913, his importing firm had sales of 380,000 and a net profit of 150,000, figures that peaked in 1916 with sales of... 

Parascandola, The Theoretical Basis of Paul Ehrlich s Chemotherapy Travis, Science as Receptor of Technology Paul Ehrlich and the Synthetic Dyestuffs Industry Doctors Have Faith in Ehrlich s 606, New York Times, February 9, 1912, p. 18 Herman A. Metz, letter to editor, Dr. Ehrlich s Remedy, New York Times, November 8, 1910, p. 8 Metz, Solving Medical Mysteries by Help of Animals, New York Times, January 28, 1912, p. SM6 Baumler, A Century of Chemistry, 33-38 Neo-Salvarsan is No. 914, New York Times, April 28, 1912, p. C3. 

Witnesses among the manufacturers included Henry Howard (Merrimac Chemical Company), Albert H. Hooker (Hooker Electrochemical Company), James T. Pardee (Dow Chemical Company), Henry Wigglesworth (National Aniline Chemical Company), Henry B. Rust (Koppers Company), Irenee du Pont (E. I. du Pont de Nemours Company), E. H. Killheffer (Newport Company), E. C. Klipstein (E. C. Klipstein Sons), Samuel Isermann (Van Dyk Company), and Herman A. Metz (Consolidated Color Chemical Company) in Senate Committee on Finance, Hearings, Dyestuffs (1920), 61-141, 155-83, 207-16, 281-326. 

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