Histological grading

The prognosis for prostate cancer patients depends on the histologic grade, the tumor size, and the disease stage. More than 85% of patients with stage Aj disease but less than 1% of those with stage D2 can be cured. 

Tumor size and the presence and number of involved axillary lymph nodes are primary factors in assessing the risk for breast cancer recurrence and subsequent metastatic disease. Other disease characteristics that provide prognostic information include histologic subtype, nuclear or histologic grade, lymphatic and vascular invasion, and proliferation indices. 

Rogalla P, Drechsler K, Kazmierczak B, Rippe V, Bonk U, Bullerdiek J (1997) Expression of HMGl-C, a member of the high mobility group protein family, in a subset of breast cancers relationship to histologic grade. Mol Carcinog 19(3) 153-156... 

Histology-grade xylene. Use for removing paraffin from paraffin tissue sections on glass slides. 

Soak tJie slide in a Coplin jar of histology-grade xylene for 5 min at room temperatnre. Transfer the slide to fresh xylene and soak for 5 min. 

Head and neck Squamous cell Carcinoma f5 41 Melle et al., 2003 Reduced annexin 1 expression correlates with histological grade. (Pedrero et al., 2004... 

Astrocytic brain tumour f2 Expression of Annexin 2 correlated with histological grade (Roseman et al., 1994)... 

G17. Gleason, D. F., and Mellinger, G. T., Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J. Urol. Ill, 58-64 (1974). 

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