Histocompatibility Minor

Robert, J., et al., Minor histocompatibility antigen-restricted CD8 T-cell responses elicited by heat shock proteins, J. Immunol., 168, 1697, 2002. 

The role of minor histocompatibility antigens in GVHD and rejection A minireview Goulmy, E., Voogt, P., van Els, C., de Bueger, M., van Rood, J. (1991). Bone Marrow Transplant, 7 Suppl 1 49-51. 

Goulmy E, Schipper R, Pool J, Blokland E, et al. 1996. Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host-disease after bone marrow transplantation. NEJM. 334 281-285. 

Roopenian D, Choi EY, Brown A. 2002. The immunogenomics of minor histocompatibility antigens. Immunol Rev. 190 86-94. 

Differences that matter Major cytotoxic T cell-stimulating minor histocompatibility antigens. Immunity 13(3), 333-344. 

Gundlach B, Wiesmiiller K-H, Junt T, Kienle S, Jung G. Walden P (1996) Specificity and degeneracy of minor histocompatibility antigen-specific MHC-restricted cytotoxic T lymphocytes, J Immunol 156 3645-3651. 

An important question concerns the effect of the minor shift on the isochore pattern. This problem has been explored on all syntenic regions shared by human and mouse, that were large enough to comprise more than one isochore. The results of this investigation (Pavli-cek et al., 2002b) indicate that the human isochore pattern is still recognizable in the mouse chromosomes after the minor shift. This will be illustrated here by considering the major histocompatibility (MHC) locus. 

Ea-C 1 Also present on l5unpho-cytes, closely linked to a minor histocompatibility complex... 

Major histocompatibility complex, MHC several closely linked genetic loci in vertebrates which encode cell-surface glycoproteins and serum proteins known as histocompatibility antigens. In adchtion to the MHC, which have been found in all vertebrates examined for them, there are other cell surface antigens which have been little studied and are referred to as minor histocompatibility antigens (complexes). 

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