High-risk structures

If concrete mixes made with high amounts of microsiUca are exposed to fire, an excessive internal water vapor pressure may develop, causing cracking, strength reduction, and occasionally explosive spalling. Such a danger exists especially in moist concretes. To prevent this, it may be necessary to add appropriate fibers to the fresh mix in high-risk structures. 

The protection potentials for seawater are described in Section 2.4. In pipelines and harbor installations, there is no limiting negative potential t/ for uncoated earbon steel or for steel provided with thiek eoatings over 1 mm, with yield points up to 800 N mm". With dynamieally highly loaded structures, the protection potential ranges in Table 16-2 should be adhered to as in the regulations [1-3] because of the risk of hydrogen-induced stress corrosion (see Section 2.3.4). 

N/A A Patients at high risk for heart failure but without structural heart disease or symptoms of heart failure. 

Men with disease fixed or invading adjacent structures other than the seminal vesicles (T4) are at very high risk for recurrence. Androgen ablation should be initiated at diagnosis instead of waiting for the onset of symptoms. 

From the wide variety of emerging pollutants of industrial origin that could be considered here, bisphenol A (BPA) and phthalate esters (PE) are of especial relevance not only because of the high volumes produced and their widespread use, but also because of their demonstrated toxicity, particularly as endocrine disrupters. Both of them have been included in the final report of the European Commission toward the establishment of a priority list of endocrine disrupter chemicals, EDCs [3], and have been rated as of high risk of exposure for human and wildlife populations. Because of their structural characteristics these compounds cannot be included in any of the groups described above, so they will be described in this section (see Fig. 10). 

Stand structure is altered rapi y in some areas by salvage logging of high-risk trees as a result, species composition is changing, and wildlife habitat is being altered. 

At high risk for HF Structural heart Structural heart disease Refractory HF... 

LAs block nerve conduction when applied locally to nervous tissue by a voltage- and frequency-dependent inhibition of sodium currents (see Voltage-gated Sodium Channels Structure and Function1). Due to this mechanism, they preferentially block hyperexcitable cells and interfere comparatively less with normal physiological sensory and motor function. However, they are not selective for pain-relevant sodium channel subtypes so that they have a relatively high risk of adverse effects associated with the central nervous and cardiovascular systems when administered systemically. Known LAs are not active when administered orally. 

The committee recognizes that the design and synthesis of molecules or structures that exhibit useful chemical recognition properties is extremely difficult, with a high risk of failure. Advanced molecular modeling methods are beginning to be applied to this area, but preliminary results are... 

In general, a medical device is defined as follows a medical device is an implant and equipment to be used either to achieve disease diagnosis, medical treatment, or disease prevention for human and animals, or to influence the physical structure and function of human and animals. Medical devices for humans may also be classified based on whether and how long the device is in contact with tissue or cells and on the degree of disjunction induced by the device when in a disabling situation. The term covers various categories, such as scissors and tweezers, with small risk to human function, to central venous catheters, artificial dialysis (human kidney), and pacemakers, with high risk to human function. 

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