Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Heterocyclic molecules

SJ paracyclophane etc.] refers to the benzene rings in the structure, i.e. [8]-paracyclophane, [2,2,2]-para-cyclophane. Systems based upon heterocyclic molecules are also known. [Pg.123]

Classify each of the following heterocyclic molecules as aromatic or not according to Fluckel s rule... [Pg.471]

Of interest, and occasional importance (in whiteness enhancers, for instance), are the fluorescent properties of heterocyclic compounds. Fluorescence is quite frequently found in the compounds relevant to this volume the acridines and acridones show it particularly often, but it appears in a number of very diverse systems. The fluorescence and phosphorescence of heterocyclic molecules have been reviewed by Schulman <74PMH(6)147). [Pg.20]

The term mesoionic was suggested originally to describe compounds of the sydnone (129) or sydnone imine (130) type (49JCS307, 50JCS1542). Since then this term has been applied somewhat indiscriminately to a variety of heterocyclic molecules which can be represented formally as zwitterions. The original, rather restrictive definition put forward by Baker and Ollis (55CI(L)910) was later made even more so by Ollis and Ramsden (76AHC(19)1), and it is this most recent definition which now appears to be the most useful. [Pg.34]

Another heterocyclic molecule that can serve as a benzyne precursor is benzothiadiazole-1,1-dioxide, which decomposes with elimination of sulfur dioxide and nitrogen. ... [Pg.595]

In addition to direct attack on the nitrogen atom which finally becomes the quaternary center, it is possible for the electrophile to attack elsewhere in the heterocyclic molecule and for a mesomeric shift to proceed to completion to give a salt. [Pg.2]

A. Electronic (Ultraviolet and Visible) Absorption Spectra The electronic absorption spectra of heterocyclic molecules have their origins in the transitions of electrons between different molecular orbitals. In general, the more these orbitals are spread out in space, the closer together are their energy levels and the longer the wavelengths... [Pg.44]

One of the more complex local anthetics in fact comprises a basic ether of a bicyclic heterocyclic molecule. Condensation of 1-nitropentane with acid aldehyde, 79, affords the phthalide, 81, no doubt via the hydroxy acid, 80. Reduction of the nitro group... [Pg.18]

The relative inaccessibility of physostigmine led to molecular dissection studies to define the parts of the molecule necessary for activity. A surprisingly simple derivative of m-hydroxy-aniline, neostigmine (40), proved to have the same activity as the complex heterocyclic molecule. In addition, this drug has found use as a cholinsterase inhibitor in pathologic conditions such as myasthenia gravis, marked by insufficient muscle tone. Reaction of m-dimethylaminophenol (37) witn pnosgene affords tne... [Pg.113]

Antidepressants are small heterocyclic molecules entering the circulation after oral administration and passing the blood-brain barrier to bind at numerous specific sites in the brain. They are used for treatment of depression, panic disorders, generalized anxiety disorder, social phobia, obsessive compulsive disorder, and other psychiatric disorders and nonpsychiatric states. [Pg.112]

Hydrazides (RCONHNH2) are highly useful starting materials and intermediates in the synthesis of heterocyclic molecules.2 They can be synthesized by hydrazinolysis of amides, esters and thioesters.3 The reaction of hydrazine with acyl chlorides or anhydrides is also well known,4 but it is complicated by the formation of 1,2-diacylhydrazines, and often requires the use of anhydrous hydrazine which presents a high thermal hazard. Diacylation products predominate when hydrazine reacts with low molecular weight aliphatic acyl chlorides, which makes the reaction impractical for preparatory purposes.5... [Pg.134]

Data are given in Table IV for heterocyclic compounds. For piperidine there is no difference between E and E, showing that the bond energies used are applicable to saturated heterocyclic molecules. Pyridine and quinoline differ from benzene and naphthalene only by the presence of one N in place of CH and, as expected, the values 1.87 v.e. and 3.01 v.e., respectively, of the resonance energy are equal to within 10 percent to the values for the corresponding hydrocarbons. [Pg.135]

The synthesis of heterocyclic compounds using transition metals and using heterocyclic compounds as intermediates in the synthesis of other organic compounds will bean additional feature of each volume. Pathways involving the destruction of heterocyclic rings will also be dealt with so that the synthesis of specifically functionalized non-heterocyclic molecules can be designed. Each volume in this series will provide an overall picture of heterocyclic compounds... [Pg.9]

Typical reaction conditions for these reagents are shown below. Propose mechanisms by which these heterocyclic molecules can function to activate carboxy groups under these conditions. [Pg.286]

DCA reactions are an important means of synthesis of a wide variety of heterocyclic molecules, some of which are useful intermediates in multistage syntheses. Pyrazolines, which are formed from alkenes and diazo compounds, for example, can be pyrolyzed or photolyzed to give cyclopropanes. [Pg.531]

Metal-mediated reductive coupling of alkenes and alkynes affords access to complicated organic structures, including carbocyclic and heterocyclic molecules, from readily available starting materials. While most of these coupling reactions were initially developed as stoichiometric processes, many selective, catalytic versions have been developed over the past decade these advancements have made reductive coupling much more attractive to synthetic chemists. [Pg.217]

In contrast to aromatic hydrocarbons, heavy-atom substitution onto carbonyl and heterocyclic molecules appears to have little effect on radiative and nonradiative intercombinational transitions. Wagner(138) has shown that as determined by the type II photoelimination, aliphatic ketones (n -> it excited states) are not sensitive to external heavy-atom perturbation. As seen previously in our discussion of type II photoelimination, aliphatic ketones undergo this cleavage from both the excited singlet and triplet states (in... [Pg.435]

Monticello, D. J., Continuous process for biocatalytic desulfurization of sulfur-bearing heterocyclic molecules. Patent No. W09219700. 1992, Nov. 12. [Pg.216]

A viscosity reducing method based on the selective cleavage of carbon sulfur bonds of aromatic heterocyclic molecules containing a sulfur heteroatom. The physicochemical properties of these heterocycles contribute to the liquid viscosity. The method comprises contacting the liquid with an effective amount of a biocatalytic agent. [Pg.299]


See other pages where Heterocyclic molecules is mentioned: [Pg.18]    [Pg.20]    [Pg.47]    [Pg.553]    [Pg.19]    [Pg.39]    [Pg.220]    [Pg.73]    [Pg.657]    [Pg.664]    [Pg.31]    [Pg.44]    [Pg.46]    [Pg.144]    [Pg.56]    [Pg.232]    [Pg.4]    [Pg.7]    [Pg.326]    [Pg.340]    [Pg.346]    [Pg.364]    [Pg.308]    [Pg.204]    [Pg.572]    [Pg.88]    [Pg.4]   
See also in sourсe #XX -- [ Pg.300 ]

See also in sourсe #XX -- [ Pg.259 ]

See also in sourсe #XX -- [ Pg.91 ]

See also in sourсe #XX -- [ Pg.91 ]

See also in sourсe #XX -- [ Pg.91 ]




SEARCH



© 2024 chempedia.info