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Fused heterocycles

As previously described, the Gould-Jacobs reaction has been applied to heterocycles fused to anilines, and to some amino-substituted heterocycles. Selectivity of N- and C-cyclization of 2-aminopyridino-methylene malonates has been mentioned (51 and 56). The normal mode of cyclization of 2-aminopyridino-methylene malonates is on the nitrogen to form a pyridopyrimidine. If an electron-donating group (EDG) is in the 6-... [Pg.432]

Asymmetric Pauson-Khand reaction in syntheses of heterocycles fused with five-member carbocyclic fragment 980PP121. [Pg.213]

Anticoagulant therapy was developed with the adventitious discovery of dicoumarol (8). A fuller discussion of the rationale for the use of such compounds is found in the chapter on Five-Mem-bered Heterocycles Fused to One Benzene Ring. The reader s attention is directed, however, at the fact that dicoumarol is a polycarbonyl compound containing a very acidic hydrogen. A series of similarly acidic 1,3-indandiones have been found to constitute an additional class of anticoagulant agents. [Pg.147]

Five-Membered Heterocycles Fused to One Benzene Ring... [Pg.313]

It is therefore not unexpected to find a similar effect in a heterocycle fused to a benzene ring. Reaction of the substituted benzothiazole, 71, with sodium hypochlorite in a mixture of sodium hydroxide and ammonia affords the sulfenamide, 72, probably by the intermediacy of the sulfenyl chloride. [Pg.326]

FIVE-MEMBERED HETEROCYCLES FUSED TO BENZENE intermediate 52 affords domperidone (66), a very... [Pg.174]

Heterocycles Fused to Other Aromatic or Heteroaromatic Rings... [Pg.245]

In this section coverage follows the general order of Part I [93AHC (57)271] in that heterocycles fused to furan will precede those fused to thiophene and pyrrole fused oxazoles will precede fused thiazoles, etc. [Pg.279]

The N,0- and N,S-heterocyclic fused ring products 47 were also synthesized under radical chain conditions (Reaction 53). Ketene acetals 46 readily underwent stereocontrolled aryl radical cyclizations on treatment with (TMSlsSiH under standard conditions to afford the central six-membered rings.The tertiary N,0- and N,S-radicals formed on aryl radical reaction at the ketene-N,X(X = O, S)-acetal double bond appear to have reasonable stability. The stereoselectivity in hydrogen abstractions by these intermediate radicals from (TMSlsSiH was investigated and found to provide higher selectivities than BusSnH. [Pg.142]

The synthesis of novel heterocycle-fused furo[3,4-d]isoxazoles via ring transformation of 2-isoxazoline-2-oxides by Lewis acids was reported <96H(42)289>. A practical application of the... [Pg.124]

In a series of three papers, Noguchi and co-workers have reported their continuing studies on the formation of heterocycle-fused azepine systems <96X13081, 96X13097, 96X13111>. A typical example is the conversion of the aldehyde 15 into the azepines 16 and 17 (Scheme 3). Xhe reaction also proceeds with imines when the dihydroazepine prior to bridging can be isolated. Mechanistic and stereochemical aspects of the reaction have been explored. [Pg.320]


See other pages where Fused heterocycles is mentioned: [Pg.89]    [Pg.330]    [Pg.393]    [Pg.165]    [Pg.166]    [Pg.167]    [Pg.168]    [Pg.169]    [Pg.170]    [Pg.171]    [Pg.172]    [Pg.173]    [Pg.175]    [Pg.176]    [Pg.177]    [Pg.178]    [Pg.179]    [Pg.180]    [Pg.181]    [Pg.41]    [Pg.42]    [Pg.246]    [Pg.89]    [Pg.361]    [Pg.409]    [Pg.410]    [Pg.411]    [Pg.412]   
See also in sourсe #XX -- [ Pg.49 ]

See also in sourсe #XX -- [ Pg.246 ]

See also in sourсe #XX -- [ Pg.49 ]




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1.2.4- Triazines fused to heterocycles with 6-and 7-membered

1.2.4- Triazines fused to two heterocyclic rings

Acridines, heterocycle-fused

Benzene-fused five-membered heterocycles

Benzene-fused heterocycles containing tellurium, selenium and sulphur

Benzo-fused five-membered heterocycles

Benzo-fused five-membered heterocycles aromaticity

Benzo-fused heterocycles

Benzo-fused heterocycles, reduction

Benzo-fused heterocycles, synthesis

Benzo-fused heterocyclic cations

Bicyclic Fused Heterocycles

Compounds containing Three or Four Fused Heterocyclic Rings (5,5,5), (5,5,6), (5,5,7), (5,6,7), and

Condensed 1,2,4-triazines: I. Fused heterocycles with three-, four-, and

Condensed 1,2,4-triazines: I. Fused heterocycles with three-, four-, and fivemembered rings

FIVE-MEMBERED HETEROCYCLES FUSED TO A BENZENE RING

Ferrocenes Containing a Heterocyclic Ring Fused to the Ferrocene

Fischer, G., Tropones, Tropolones, and Tropylium Salts with Fused Heterocyclic

Five-Membered Heterocycles Fused to Benzene

Five-Membered Heterocycles Fused to One Benzene Ring

Five-Membered Heterocyclic Rings and Their Fused Derivatives

Five-membered heterocycles fused with

Fused Five-Membered Heterocycles

Fused Heterocycles containing One Oxygen or Sulphur Atom

Fused Heterocyclic Compounds

Fused Heterocyclic Rings

Fused heterocycles sharing at least one heteroatom

Fused heterocycles systems

Fused heterocycles, synthesis

Fused heterocyclic

Fused heterocyclic

Fused heterocyclic systems

Fused nitrogen heterocycles

Fused quinoline heterocycles

Fused to a Second Heterocyclic Ring

Fused to heterocycles with 6-and

Fused to heterocycles with 6-and 7-membered rings

Fused to other Nitrogen-containing Heterocycles

Fused to two heterocyclic rings

Fused-Ring Five-Membered Heterocycles Indoles and Purines

Fused-Ring Heterocyclic Compounds

Fused-ring five-membered heterocycles

Fused-ring heterocycle

HETEROCYCLES FUSED TO TWO AROMATIC RINGS

Heteroaromatic compounds fused heterocycles

Heterocycle-fused -catalyzed synthesis

Heterocycles fused to a benzene ring

Heterocyclic Ring-Fused 1,2-Thiazines

Heterocyclic aromatic compounds fused

Heterocyclic fused TCNQ acceptors

Heterocyclic fused spirocyclic

Lithiation benzo fused heterocycles

Medicinal interest fused heterocycles

Medium ring size heterocycles fused with

Microwave irradiation fused heterocycles

Naming fused heterocycles

Nomenclature fused heterocyclic compounds

Numbering peripheral, fused heterocycles

Other Fused Heterocyclic Compounds

Other Seven-Membered Heterocycles Fused to a Benzene Ring

Oxidative cleavage of fused heterocyclic ring systems

Palladium Catalysis in the Synthesis of Benzo-Fused Heterocycles

Polycyclic fused nitrogen heterocycles

Purines Fused with Five-Membered Heterocycles

Pyrimidines heterocyclic fused

SEVEN-MEMBERED HETEROCYCLIC RINGS FUSED TO BENZENE

Selenophens Fused to Six-membered Heterocyclic Aromatic Rings

Six-Membered Heterocycles Fused to One Benzene Ring

Spiro-fused heterocycles

Spiro-fused heterocycles, formation

Steroids Having Fused Heterocyclic Rings

Stille reactions fused heterocycles

Synthesis of Fused Heterocycles

Synthesis of Quinoxalines from Various Fused Nitrogen-Containing Heterocycles Without a Pyrazine Fragment

Trivial names fused heterocycles

Tropolones with fused heterocyclic rings

Tropolones with fused heterocyclic rings structure, reactivity, and application

Tropolones with fused heterocyclic rings synthesis

Tropones with fused heterocyclic rings

Tropones with fused heterocyclic rings structure, reactivity, and application

Tropones with fused heterocyclic rings synthesis

Tropylium salts with fused heterocyclic rings

Tropylium salts with fused heterocyclic rings synthesis

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