HepG2 human hepatoma cells

The follicles are used to treat asthma and cough and to mitigate painful swollen breasts. A paste of the leave is applied to contusion. Essential oil distilled from the follicles induced apoptotic death in HepG2 human hepatoma cells in a concentration- and time-related manner, and inhibited tumor development of mice inoculated with Huh-7 human hepatoma cells (33). 

Paik SY, Koh KH, Beak SM, Paek SH, Kim JA. The essential oils from Zanthoxylum schinifolium pericarp induce apoptosis of HepG2 human hepatoma cells through increased production of reactive oxygen species. Biol Pharm Bull 2005 28 802-807. 

Burezynski, M.E., McMillian, M., Ciervo, J., Li, L., Parker, J.B., Dunn, R.T., Hicken, S., Farr, S. and Johnson, M.D. (2000) Toxicogenomics based discrimination of toxic mechanism in HepG2 human hepatoma cells. Toxicological Sciences, 58, 399-415. 

Sakakibara, Y., Katafuchi,)., Takami, V., N akayama, T., Suiko, M Nakajima, H., and Liu, M.-C. (1997). Mangancse-depedent DOEA/tyroslne sulfation in HepG2 human hepatoma cells. Bioefnm. Biirpfs. Acts 1335,102-106. 

SILAC-based proteomics approach was successfully used to identify a total of 63 differentially expressed proteins between a HepG2 human hepatoma cell line and an immortal hepatic cell line L02 [83]. Among these differentially expressed proteins, phosphoglyc-erate mutase was found highly upregulated and might play important role in hepatocarcinogenesis, which demonstrated the remarkable power of this SILAC platform in biomarker discovery. 

HepG2 Human hepatoma cell line Hepatotoxicity/metabolism... 

Shown are the measured number of receptors per cell RT, the association rate constant kf, the dissociation rale constant k and the equilibrium dissociation, constant Ka = kT/k,. The lime required to reach 95% of equilibrium receptor binding when no bound receptors are initially, present, is calculated from r,5 = - ln(0.05)/[Ar( 1 + La/KD)] for the case of /. = Ka. HepG2 - human hepatoma cell line ... 

Maness. S. C,. McDonnell, D. P., and Gaido, K. W. (1998). [nhihilion of androgen reccptor-depcndcnt transcriptional activity by DDT isomers and mcthoxychlor in HepG2 human hepatoma cells. Toxicol. Appl. Fharmacol. ISl, 135-142. 

Burczynski M E, McMillian M, Ciervo J, et al. (2000). Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells. Toxicol. Sci. 58 399-415. 

Lee YS, Jin DQ, Kwon EJ, Park SH, Lee ES, Jeong TC, Nam DH, Huh K, Kim JA (2002) Asiatic acid, a triterpene, induces apoptosis through intracellular Ca release and enhanced expression of p53 in HepG2 human hepatoma cells. Cancer Lett 186 83-91... 

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