Hemoglobin carbon monoxide combining with

Since the reactions of both carbon monoxide and oxygen with hemoglobin are reversible, the concentrations of the two gases, in addition to the relative strengths of their binding to hemoglobin, affect how much hemoglobin will be combined with either molecule. 

Asphalt Hydrocarbon material ranging in consistency from heavy liquid to a solid. Most common source is residue left after fractional distillation of crude oils used primarily for surfacing roads. Asphyxia Suffocation from lack of oxygen. Chemical asphyxia is produced by a substance, such as carbon monoxide, that combines with hemoglobin to reduce die blood s capacity to transport oxygen. Simple asphyxia is the result of exposure to a substance, such as carbon dioxide, that displaces oxygen. 

Carbon monoxide (CO), a colorless, odorless gas, is responsible for more than half of yearly deaths due to poisoning worldwide. CO has an approximately 250-fold greater affinity for hemoglobin than does oxygen. Consequently, relatively low levels of CO can have substantial and tragic effects. When CO combines with hemoglobin, the complex is referred to as carboxyhe-moglobin, or COHb. 

AFFINITY. The tendency of an atom or compound to react or combine with atoms or compounds of different chemical constitution. For example, paraffin hydrocarbons were so named because they are quite unreactive, the word paraffin meaning very little affinity." The hemoglobin molecule has a much greater affinity for carbon monoxide Ilian for oxygen. The free energy decrease is a quantitative measure of chemical affinity. 

PREFERENTIAL. Descriptive of the selectivity of action, either chemical or physiochemical. exhibited by a substance when in contact with two other substances it may be due either to chemical affinity or to surface phenomena. An example of a preferential chemical combination is that of hemoglobin with carbon monoxide, with which it unites 200 times as readily as it does with oxygen when expose to a mixture of the two. Such phenomena as adsorption, corrosion, and the wetting of dry powders by liquids are other examples,... 

Carbon monoxide Motor vehicle emissions Burning fossil fuels Incomplete combustion Combines with hemoglobin to form carboxyhemoglobin, poisonous Asphyxia and death... 

Carbon monoxide, like cyanide, poisons by combining with the heme of both cytochrome oxidase and hemoglobin (the Fe forms). This may be treated with hyperbaric oxygen, which competes with carbon monoxide for the hemoglobin, in addition to delivering to the tissues oxygen dissolved in the plasma. 

A pollutant may combine with a cell constituent and form a complex. This often leads to impaired function. For example, carbon monoxide (CO) in the blood readily binds to hemoglobin (Hb), forming carboxyhemoglobin (COHb) as shown below ... 

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