Harden, Arthur

Harden, Arthur. Alcoholic Fermentation. London, 1923. Henrici, A. T. Molds, Yeasts, and Actinomycetes. New York, 1930. 

On Dalton s symbols, see W. W. Haldane Gee, Hubert Frank Coward, and Arthur Harden, "John Dalton s Lectures and Lecture Illustrations," Memoir No. XII in Mem.Manchester LPS 59 (191415), esp. 4166. J. J. Berzelius, "Essay on the Cause of Chemical Proportions, and on some Circumstances relating to Them Together with a Short and Easy Method of Expressing Them," Annals of Philosophy 2 (1813) 443454, and 3 (1814) 4352. Also see, Crosland, 268275. 

Gee, W. W. Haldane, Hubert Frank Coward, and Arthur Harden. "John Dalton s Lectures and Lecture Illustrations." Mem.Manchester LPS 59, XII (191415). 66 pp. 

Arthur Harden Great Britain fermentation of sugar and sugar enzymes... 

Daltons lecture is printed in Henry E. Roscoe and Arthur Harden, A New View of the Origin of Daltons Atomic Theory [London, 1896], facsimile reprint (New York Johnson Reprint Corporation, i960), 13-18, at 14. 

Arthur Harden and Hans A. S. von Euler-Chelpin Chemistry Fermenting enzymes, fermentation of sugars... 

HARDEN. SIR ARTHUR (1865-1940). An English chemist who won the Nobel prize in chemistry in 1929 along with Hans von-Euler C helpin. He discovered fermentation enzy mes and demonstrated the structure of zymase, llis fermentation work proved how inorganic phosphates speeded the process. Bora in England, he received his doctorate in Germany. 

Sir Arthur Harden sent eight letters from British biochemists proposing more or less important modifications. 

Arthur Harden, Hans von Euler-Chelpin For their investigations on the fermentation of sugar and fermentative enzymes. ... 

Hans von Euler is generally recognized as the first to establish the chemical structure of NAD (Metzler, p. 468). Von Euler and Arthur Harden shared the 1929 Nobel Prize in physiology or medicine for the discovery of coenzymes (including NAD). Later von Euler showed that NAD contains two units of the sugar ribose, two phosphate groups, one adenine unit, and... 

Henry Taube 1929 Arthur Harden, Hans von Euler-Chelpin... 

In 1929, the Nobel Prize in chemistry was shared by Arthur Harden and Hans von Euler-Chelpin (1873-1964) for their work, culminating... 

Arthur Harden and William J. Young (see chapter 1) showed three decades earlier that the fermentation enzyme in yeast is separable into a colloidal fraction ( zymase ) and a heat-stable, water-soluble fraction ( cozymase ). Tbe two fractions separately show no enzymatic activity. Warburg later demonstrated the activity of cozymase and, in 1936, nicotinic acid (niacin or vitamin Bj) was found to be its hydrolysis byproduct. In that year, Hans von Euler-Chelpin published the structure of nicotinamide adenosine dinucleotide (NAD ) and its phosphate derivative (NADP ) (see the structure below). Euler-Chelpin shared the 1929 Nobel Prize in chemistry with Arthur Harden for their independent studies on cozymase, seven years before publication of the NAD structure. In contrast to FMN and FAD, NAD, and NADP only transfer two electrons (H + 2e") at a time (see the structure below). 

British biologist Arthur Harden (1865-1940) discovers coenzymes. 

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