Growth spurt, adolescent

In the vitamin D deficiency disease rickets, the bones of children are undermineralized as a result of poor absorption of calcium. Similar problems occur in adolescents who are deficient during their growth spurt. Osteomalacia in adults results from demineralization of bone in women who have little exposure to sunlight, often after several pregnancies. Although vitamin D is essential for prevention and treatment of osteomalacia in the elderly, there is little evidence that it is beneficial in treating osteoporosis. 

As mentioned earlier, the emerging consensus is that the growth spurt in adolescence after psychostimulant discontinuation compensates for any earlier effect on growth velocity. Thus, eventual height is not compromised. What is less clear is whether this compensatory growth spurt would hold true for those continued on psychostimulants through adolescence. Hence, clinicians have an increased responsibility to determine whether a medication has had a positive effect and should continue it during adolescence only when such an effect has been satisfactorily documented. 

These medications are often discontinued when the child reaches puberty. One reason for this practice is that adolescents may be more likely to abuse psychostimulants. There is also the aforementioned issue about the potential developmental effects (e.g., growth spurt) of continuing psychostimulants during... 

Three adolescent boys with chronic renal insufficiency, treated with somatropin during the pubertal growth spurt, developed severe hyperparathyroidism (35). It is unclear whether this was coincidental or whether growth hormone and sex steroid hormones had a synergistic effect. 

Frost HM. Perspectives On increased fractures during the human adolescent growth spurt. Summary of a new vital-biomechanical explanation. J Bone Miner Metab. 1997 15 115-121. 

Hyperutilization of folic acid may occur when the rate of cellular division is increased as is seen during pregnancy hemolytic anemia myelofibrosis mahgnancy chronic inflammatory disorders such as Crohn s disease, rheumatoid arthritis, or psoriasis long-term dialysis burn patients and growth spurts seen in adolescence and infancy. This can lead to anemia, particularly when the daily intake of folate is borderline, resulting in inadequate replacement of folate stores. 

Secondly, injuries to the paediatric spine should be followed up over a long time as they demonstrate variable remodelling and may develop progressive deformity especially during the adolescent growth spurt (McPhee 1981 Pouliquen et al. 1997). 

The requirement for the vitamin based on a body-weight increment is thought to decline rapidly following birth and increases only slightly during the adolescent growth spurt. This temporal relationship depicted in Fig. 2 is taken from an earlier publication (FAO/WHO, 1967). For the adult, the recommended dietary intake (RDI) per day is 12 RE per kg or about one-fifth that on a body-weight basis of the 3-month-old infant (FAO/WHO, 1967). 

The efficiency of calcium absorption is highest during infancy (approximately 60%), and the amount absorbed from breast milk does not appear to be affected by calcium consumed in solid foods. During the growth spurt of adolescence, calcium retention and accretion increase to peak at approximately 200-300 mg per day in girls and boys. 

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