Growth factors study

M17. Merimee, T. J., Zapf, J., and Froesch, E. R., Insulin-like growth factors. Studies in diabetics with and without retinopathy. N. Engl. /. Med. 300, 527-530 (1983). 

Pathway Overview Anabolic Growth Factors/Cytokines Catabolic Growth Factors/Cytokines Hormones Mechanotransduction Dual Growth Factor Studies Conclusion References... 

Studies with fenretinide in woman with stage I breast cancer did not show an overall effect of decreasing the risk of contralateral breast cancer. A protective effect could only be observed in premenopausal women, probably due to the modulation of the insulin-like growth factor 1 (IGF-1) by fenretinide in this population. 

The serum requirement of many transformed animal cells is also reduced. The reduction in the serum requirement can, in many cases, be explained by a loss of some of the cells hormone, growth factor or adhesion requirements. The altered hormone, growth factor, or attachment requirements can be studied by growing the cells in serum-free medium. 

The most important survival and growth factor for mast cells is the KIT Ugand stem cell factor (SCF) [12], The hypothesis of early studies, that SCF might be elevated in skin lesions associated with mastocytosis [13], however, was not confirmed by later studies on SCF levels in skin and blood, at least for adult patients [14],... 

Martin C, Solders G et al (2000) Antiretroviral therapy may improve sensory function in HIV-infected patients a pilot study. Neurology 54(11) 2120-2127 Masjuan J, Corral I et al (1997) Mycobacterial acute lumbosacral polyradiculopathy as the initial manifestation of AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 15(2) 175 McArthur JC, Yiannoutsos C et al (2000) A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection. AIDS Clinical Trials Group Team 291. Neurology 54(5) 1080-1088... 

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