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Epidermal growth factor therapy studies

Boron neutron capture therapy (BNCT) offers a potential method for localized destruction of tumor cells. The technology is based on the nuclear reaction between thermal neutrons and boron-10 (lOB) to yield alpha particles and lithium-7 nuclei. The destructive effect of this reaction is limited to a range of about the diameter of a single cell. In order for BNCT to be effective in cancer therapy, there must be selective delivery of an adequate concentration of lOB to tumors. Various types of antibodies as well as epidermal growth factor have been utilized to investigate receptor-mediated boron delivery however, in vivo studies have demonstrated that only a small percentage of the total... [Pg.262]

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See also in sourсe #XX -- [ Pg.4 , Pg.658 ]

See also in sourсe #XX -- [ Pg.658 , Pg.666 ]



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