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Growth factors carcinogenicity studies

Carcinogenicity studies are not considered appropriate. However, product specific properties may necessitate testing (e.g. growth factors, immunosuppressive properties). Further, the ability to stimulate growth of normal or malignant cells expressing the receptor should be taken into consideration. [Pg.800]

G is thought to be responsible for the anti-carcinogenic activity of China-rose hibiscus (Hibiscus rosa-sinensis) extract, and a recent study has shown that gentisic acid is a Fibroblast Growth Factor (FGF) inhibitor [60, 61]. [Pg.1962]

Since many members of this group are protein growth factors with mitogenic activity, one of the main issues of concern is the approach towards the evaluation of carcinogenic potential. Hence, the relevance of classical genotoxicity and carcinogenicity studies for these products needs to be considered. [Pg.135]

See other pages where Growth factors carcinogenicity studies is mentioned: [Pg.147]    [Pg.137]    [Pg.414]    [Pg.157]    [Pg.115]    [Pg.364]    [Pg.344]    [Pg.406]    [Pg.460]    [Pg.661]    [Pg.965]    [Pg.249]    [Pg.256]    [Pg.1422]    [Pg.2444]    [Pg.797]    [Pg.1217]    [Pg.316]    [Pg.448]    [Pg.225]    [Pg.232]    [Pg.129]    [Pg.753]    [Pg.797]    [Pg.23]    [Pg.406]    [Pg.570]    [Pg.182]    [Pg.135]    [Pg.459]    [Pg.468]    [Pg.141]    [Pg.123]    [Pg.309]    [Pg.585]    [Pg.78]    [Pg.131]    [Pg.517]    [Pg.298]    [Pg.78]    [Pg.26]    [Pg.27]    [Pg.164]    [Pg.126]    [Pg.221]   
See also in sourсe #XX -- [ Pg.403 , Pg.408 ]

See also in sourсe #XX -- [ Pg.25 ]



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Carcinogenic study

Growth factors study

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