Grooming Analysis

Three treated cats were sacrificed 0.5, 1, 2, 5, and 10 days after treatment. Radioactivity in urine and feces collected over the 10-day period accounted for 28% and 19% of the applied dose, respectively, but no radioactivity was detected in expired air. Radioactivity in analyzed tissues reached maximal levels at 24 hours (accounting for 8.7% of the applied dose). These data are inadequate for quantitative measurements of the extent of dermal absorption of TOCP, because a significant traction of the applied radioactivity was not accounted for in the analysis, and some of the TOCP may have been ingested by the cats during grooming. 

Lerner and Mills (JjO reported the presence of 0 -monoacetyl-morphine as a common constituent in heroin and suggested that the ratio of heroin to monoacetylmorphine would not change during adulteration. Others have dealt primarily with the identification of the adulterants present, either other drug substances or sugars (6,7). Grooms (j3) and Miller (9) have attempted to include the analysis of adulterants with the presence of monoacetylmorphine. In each of these cases, the resolution of the various components was insufficient to provide good quantitative data. 

More recently, studies have applied the probability of extinction as an endpoint to extrapolate short-term effects on long-term population consequences. Based on population viability analysis (Boyce 1992 Groom and Pascual 1997), population size is projected into the future using demographic rates and models that incorporate stochastic effects (Snell and Serra 2000). In practice, it would be difficult to determine extinction rates experimentally due to the need to conduct experiments over multiple generations. Thus, the probability of extinction is typically modeled using the instantaneous rate of increase (Snell and Serra 2000). 

Groom MJ, Pascual MA. 1997. The analysis of population persistence an outlook on the practice of viability analysis. In Fiedler PA, Karevia PM, editors. Conservation biology for the coming decade. New York (NY) Chapman Hall, p 4-27. 

Disctission. In the opinion of Groom Pristera (Ref 15, pp 4-5), although the Brit ERDE method is applicable to all LA s and is the simplest (because it does not require any special equipment),it is undesirable because it is very tedious and because Ag azide pptd in the course of analysis is a very sensitive... 

Gonda I, Kayes JB, Groom CV, Fildes FJT. In StanleyWood N, Allen T, eds. Particle Size Analysis 1981 Proceedings of the Fourth Particle Size Analysis Conference. Chichester, UK Wiley, 1982 31. 

Hopkins, A. L., Groom, C. R. Target analysis a priori assessment of dmggabiUty. Ernst Schering Res. Found. Workshop. 2003, 42(11—17). 

A.L. Hopkins, C.R. Groom, Target analysis a priori assessment of druggability, Ernst Schering Research Foundation Workshop, Berlin, 2003, 42. 

See Meyr et al. (2008) and Stadtler (2005). Note that there is a lot of work from numerous scientific perspectives labelled with SCM, see Groom et al. (2000) for a detailed analysis and categorization of SCM approaches. Based on this classification scheme this work reviews SCM approaches at a network level modelling material flows. 

Hill A.G., Groom R.C.,VinanskyR.P. et al. 1985. On-line or off-line blood gas analysis Gost vs. time vs. accuracy. Proc. Am. Acad. Cardiovasc. Perfusion 6 148. 

Groom, J., Chung, D., Young, J., and Westpheling, J. (2014) Fleterologous complementation of a pyrE deletion in Caldicellulosiruptor hydrothermalis generates a new host for the analysis of biomass deconstruction. Biotechnol Biofuels, 7, 132. 

Fentress, J. C., 1968, Interrupted ongoing behaviour in two species of vole (Microtus and Clethrionomys brittanicus) II. Extended analysis of motivational variables underlying fleeing and grooming behaviour, Anim. Behav. 16 154-167. 

Joseph, M. H., Baker, H. F., and Ridley, R. M., 1981, Analysis of CSF amine metabolites and precursors including tryptophan, 5-HIAA and HVA by HPLC using fluorescence and electrochemical detection in primates effect of probenecid, in Central Neurotransmitter Turnover C. Pycockand P. V. Taberner, eds.), pp. 162-167, Groom-Helm, London. 

Stone, H. M., and Groom, P. S. Techniques of Blood Alcohol Analysis. 

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