GRID analysis

In 1993, we reported on a study of nine normal subjects using a wearable continuous monitoring system.17 This was the first application of error grid analysis... 

Figure 1.7 Clarke error grid analysis plot of the data of Figure 1.6.

Clarke WL, Anderson A, Farhy L, Breton M, Gonder-Frederick L, Cox D, Kovatchev B. Evaluating the clinical accuracy of two continuous glucose sensors using continuous glucose-error grid analysis. Diabetes Care 2005, 28, 2412-2417. 

Figure 3.2 The effect of prolonged subcutaneous implantation on biosensor function. Blood glucose values shown in solid circles and glucose sensor values in the continuous lines. The early study (top panel), but not the late study (bottom), shows excellent sensor accuracy and minimal lag between blood glucose and sensed glucose values. MARD (mean absolute relative difference) refers to a sensor accuracy metric. EGA refers to the Clarke error grid analysis accuracy metric.

The different manufacturers publish their own results in their user manuals. Mean absolute relative difference and bias results from the three manufacturers are shown in Table 5.2. The MARD measures indicates the average difference while the direction of the difference and the bias indicates if the differences are uniform or skewed to positive or negative values. The Clarke error grid analysis for the three manufacturers (Table 5.3) shows a wide difference in A zone results between the... 

Clarke error grid analysis of a study of 15 diabetic rats showed the percentage of readings that fell into the clinically correct regions (Zones A and B) increased from 92% to 96% when applying the Z-score rejection criteria.38 During the long-term implantation (25 4 days), Z-score calculations removed 32% of the individual sensor data from six fully implanted four-sensor arrays.39... 

Finally, the DT/MH AgFON was evaluated in vivo. A representative Clarke error grid analysis of a single rodent is shown in Figure 15.11. All measurements were taken from a single spot on the implanted DT/MH-functionalized AgFON surface. 

Human thymidylate synthase (TS) A 5-substituted lH-benzo cd indol-2-one scaffold was designed de novo based on a key interaction pattern identified from previous X-ray analyses, and on a GRID analysis of the TS crystal structure. X-ray analysis of the complex with a newly designed, low micromolar derivative revealed unmet interactions, and suggested the replacement of a lactam carbonyl by an amidine functionality, ultimately leading to a low nanomolar TS inhibitor selected for clinical trials. i36 ... 

H. Qian, S. R. Nassif, S. S. Sapatnekar. Power Grid Analysis using Random Walks. IEEE Trans, on Computer-Aided Design of Integrated Circuits and Systems, Vol. 24, No. 8, Aug. 2005, pp. 1204- 1224. 

Fig 1 4 25 Plane-strain bending in 50 mm (2 in.) thick 5051-T5 Al. (a) Parent metal bent to 27°, with cracks initiating on the ten-" sile surface, (b) Friction stir processed 5051-T5 Al bent to 85° without cracking. Circle grid analysis of the surface strains showed that the negative minor strain at the crown was less than 1 %. 

Error grid analysis has recently been extended for the evaluation of continuous glucose monitoring sensors. Kovatchev BP, Gonder-Frederick LA, Cox DJ, and Clarke WL. 2004. Evaluating the accuracy of continuous glucose-monitoring sensors. Diabetes Care 27 1922-1928. 

The experimental distribution of the major and minor true strains obtained from circle grid analysis in the principal strain space is shown in Figure 8.6. The open markers refer to experimental strains that were taken along the meridional direction of the SPIF benchmark parts while the solid markers refer to experimental strains at failure. The latter were obtained from grid-elements placed just outside the crack since they represent the condition of the thinned sheet at the onset of fracture. 

Dunne et al. [489] 2015 Accu-Chek Active Accu-Chek Performa OneTouch Select Simple Freestyle Freedom c YSI used as reference method for all systems Consensus Grid analysis... 

Kovalchev BP, Wakcman CA, Breton MD, Kost GJ, Louie RE, Tran NK, Klrmoff DC (2014) Computing the surveillance error grid analysis procedure and examples. J Diabetes Sci Technol 8(4) 673-684... 

Based in clinical psychology and personality theory, repertory grid analysis is a structured and theoretical form of interview method. Subjects group concepts and justify how the groups are similar and dissimilar. Although a simple technique it does require some familiarity for effective application. 

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