Grape juice resveratrol

Romero-Perez AI, Ibern-Gomez M, Lamuela-Raventos RM and de la Torre-Boronat MC. 1999. Piceid, the major resveratrol derivative in grape juices. J Agric Food Chem 47(4) 1533—1536. 

Rimando et al., 2004 Sobolev and Cole, 1999 Tokusoglu et al., 2005]. In an adult Spanish cohort resveratrol and piceid, trans and czls-forms, were evaluated. Estimated median and mean of resveratrol and piceid were 100 and 933 pg/day, respectively, of which 98.4, 1.6, and less than 0.1% come from wines, grape and grape juice, and peanuts, pistachios, and berries, respectively [Zamora-Ros et al., 2008]. 

Meng X, Maliakal P, Lu H, Lee MJ, Yang CS. 2004. Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice. J Agric Food Chem 52 35-942. 

Wang Y, Catana F, Yang Y, Roderick R, Breemen RB. 2002. An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and wine. J Agric Food Chem 50 431 435. 

In grapes, and derived food products (grape juice, wine), the presence of the antioxidant stilbenoid resveratrol (Fig. 5) has also been reported [23-26]. 

Absorption of trans-resveratrol and other related compounds in rats was investigated [36]. Male Wistar rats (350 g) were used in a bioavailability study of [ H]trans-resveratrol administered by gavage together with (+ )-catechin, quercetin, and unlabeled trans-resveratrol in matrices of 10% ethanol, V8 vegetable homogenate mixture, and white grape juice. Whole blood, blood serum, urine, feces, and tissue... 

It is well known that drinking wine and grape juices will reduce cardiovascular, cerebrovascular, and peripheral vascular risks due to the presence of resveratrol. As a natural antioxidant, resveratrol is able to prevent LDL oxidation, scavenge intracellular reactive oxygen species, lower the oxidative stress, and induce NO synthesis. Resveratrol modulates various aspects of cardiovascular diseases and is effective against atherosclerosis, hypertension, ischemia reperfusion injury and heart failure, and many other cardiac dysfunctions [111]. 

Moreover, numerous studies have been developed on CHD patients. The intake of red grape polyphenol extract - which contains epicatechin, catechin, gallic acid, trans-resveratrol, s-viniferin, rutin, quercetin, p-coumaric, and ferulic acid -improved the endotheUal function in CHD patients. Similar results have been foimd for red grape juice [123]. Hypercholesterolemic patients were asked to consume red grape juice (500 mL/day) and red wine (250 mL/day) for 14 days. Results showed increased brachial artery flow-mediated dilation in both cases. However, increased endothelium-independent vasodilation was observed only in red wine-drinking patients [124]. Similar results and the same conclusions were drawn from a similar study on red grape juice. The daily ingestion of moderate... 

Resveratrol Wine, grape juice, and grape seed capsules RP-HPLC Four-channel ED (GCE) [129]... 

Zhu, Y., Coury, L.A., Long, H. et al. (2000) Liquid chromatography with multichannel electrochemical detection for the determination of resveratrol in wine, grape juice, and grape seed capsules with automated solid phase extraction. J. Liq. Chromatogr. Related TechnoL, 23, 1555-1564. 

A compound that has attracted wide interest recently is resveratrol, 12.4. It is found in red grape skins, grape juice, and red wine, and increases longevity in simple organisms such as fruit flies and worms, and also obese mice. Past studies have focused on its effect on enzymes called sirtuins that remove acetyl groups from proteins, but recent work suggests that resveratrol blocks phosphodiesterase enzymes. Like many natural products, it has a number of different effects, and it remains unclear as to which are crucial in its anti-aging effects. 

Because grape skins are in longer contact with the juice when red wine is being made, more resveratrol is found in red wine than in white wine. In laboratory tests resveratrol increases the level of the good High Density Lipoproteins and also lowers platelet... 

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