Gram-positive bacteria streptococci

Employed as a sodium salt, fusidic acid (Fig. 5.14B) is achve against many types of Gram-positive bacteria, especially staphylococci, although streptococci are relatively resistant. It is employed in the treatment of staphylococcal infections, including strains resistant to other antibiotics. However, bacterial resistance may occur in vitro and in vivo. 

The chicken intestinal microbiota is composed principally of Gram-positive bacteria (Gong et al., 2002). The lactobacilli are predominant in the small intestine (with smaller numbers of streptococci and enterobacteria), whereas the caecal flora is composed mainly of anaerobes and fewer numbers of facultative bacteria. Predominant cultured flora of the ileum of chicken include Lactobacillus, Streptococcus, E. coli and Eubacterium, while Eubacterium and Bacteroides dominated the caecum flora. 

In healthy individuals URT flora multiplies in gastric aspirate during treatment with antisecretory compounds and in particular proton pump inhibitors [34, 40, 44], This concerns viridans streptococci, coagulase-negative staphylococci, Haemophilus sp., diphtheroids, Moraxella sp., lactobacilli, and other streptococci, most of which are Gram-positive bacteria. With dedicated measures anaerobic species of oral origin are also recovered [66]. 

Thiazole cephalosporin LB 11058, 434, demonstrated a broad antibacterial spectrum and was highly active against Gram-positive bacteria, particularly against multidrug-resistant staphylococci and streptococci <2004AAC53>. 

CAS 4564-87-8. C42H67N016. An antibiotic isolated from products of Streptomyces halstedii when grown in suitable media by the deep-culture method. It inhibits growth of certain Gram-positive bacteria such as staphylococci, pneumococci, and hemolytic streptococci. Mp 214C. 

CAS 114-07-8. C37H67NOB. An antibiotic produced by growth of Streptomyces erythreus Waksman. It is effective against infections caused by Gram-positive bacteria, including some 3-hemolytic streptococci, pneumococci, and staphylococci. 

Infection. Vancomycin (18)is a relatively small glycoprotein derived from Nocar-dia orientalis, which is well known for its activity against Gram-positive bacteria including Streptococci, Corynebacteria Clos-tridia. Listeria, and Bacillus. 

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