Goodpasture syndrome

Hematologic diseases autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura, pernicous anemia Kidney disease Goodpasture syndrom, lipoid nephroses, minimal change glomerulonephritis Diseases of the gastrointestinal tract autoimmune chronic active hepatitis, autoimmune atrophic gastritis, Crohn s disease, ulcerative colitis... 

Goodpasture syndrome 438 G protein(s) 534, 557—561 bovine brain Gj 560s function, scheme 557 monomeric 558... 

Yokoo, T., Ohashi, T., Utsunomiya, Y., Shen, J. S., Hisada, Y., Eto, Y., Kawamura, T. and Hosoya, T. (2001). Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Goodpasture syndrome. Blood 98, 57-64. 

Kalluri R, Wilson CB, Eber M, Gunwar S, Chonko AM, Neilson EG, Hudson BG. Identification ofthe alpha 3 chain of type IV collagen as the common autoantigen in antibasement membrane doiseaseand Goodpasture syndrome. J Am Soc Nephrol 1995 6 1178-1185. 

Kalluri R, Gattone VH 2nd, Noelken ME, Hudson BG. The a 3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Proc Natl Acad Sci USA 1994 91 (13) 6201 -6205. 

Kalluri R, Cantley LG, Kerjaschki D, Neilson EG. Reactive oxygen species expose cryptic epitopes associated with autoimmune goodpasture syndrome. J Biol Chem 2000 275 20027-20032. 

Goodpasture syndrome Grave s disease Guillain-Barre syndrome... 

Kalluri R, Danoff TM, Okada H, et al. Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice. J CUn Invest 1997 100(9) 2263-2275. 

Kelly PT, Haponik EF. Goodpasture syndrome molecular and clinical advances. 

KaUuri R, Petrides S, Wilson CB, et al. Anti-a 1(IV) collagen autoantibodies associated with lung adenocarcinoma presenting as the Goodpasture Syndrome. Ann Int Med 1996 124(7) 651-653. 

Malignant transformation (e.g., liver adenomas) and other extrarenal => US, CT/MRI manifestation of a systemic disease (e.g., Goodpasture syndrome, etc.)... 

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