Gold therapy in rheumatoid arthritis

Gold therapy in rheumatoid arthritis-final report of a multi-centre controlled trial. Empire Rheumatism Council. Ann Rheum Dis... [Pg.151]

The Research Sub-Committee of the Empire Rheumatism Council.Gold therapy in rheumatoid arthritis. Final report of a multicenter controlled trial. Ann Rheum Dis 1961 20 315-333. [Pg.472]

Menard FIA, Beaudet F, Davis O, Flarth M, PercyJS, Russell AS,Thompson M. Gold therapy in rheumatoid arthritis. Interim report of the Canadian multicentre prospective trial comparing sodium aurothiomalate and auranofin. J Rheumatol 1982 9 179-183. Felix-Davies DD, Stewart AM, Wilkinson BR, Bateman JR, Delamere JP. A12-month comparative trial of auranofin and D-penicil-lamine in rheumatoid arthritis. Am J Med 1983 75(6A) 138-141. [Pg.475]

Cervi PL, Wright P, Casey EB. Audit of full blood count monitoring in patients on longterm gold therapy for rheumatoid arthritis. Ir J Med Sci 1992 161(3) 73. ... [Pg.1528]

Gibson J, McGirr EE, York J, Kronenberg H. Aplastic anemia in association with gold therapy for rheumatoid arthritis. Aust NZ J Med 1983 13 130-135. [Pg.472]

Halla JT, Cassidy J, Hardin JG. Sequential gold and penicillamine therapy In rheumatoid arthritis. Am J Med 1982 72 423-426. [Pg.477]

Davis, ., Turner, R., Collins, R. and Kauf-mann,J. (1976) Comparison of fenoprofen calcium and aspirin therapy during gold induction in rheumatoid arthritis. Clin. Pharmacol. Ther., 19, 105. [Pg.100]

The disease-modifying agents used in rheumatoid arthritis are associated with a number of side effects that could influence rehabilitation. Some of these drugs, such as the gold compounds and methotrexate, may cause headache and nausea, which may be bothersome during the therapy session. Joint pain and swelling may also occur with drugs such as methotrexate and peni-... [Pg.231]

Chrysiasis, or gold deposition in various tissues of the body, can occur in the conjunctiva after gold injection for rheumatoid arthritis and appears as irregular brownish deposits in the cornea and superficial layers of the conjunctiva. No deposits are found in the skin of the lid. Conjunctival changes associated with gold treatment are generally benign. Discontinuation of therapy usually eliminates these effects. [Pg.713]

Kean WF, Bellamy N, Brooks PM. Gold therapy in the elderly rheumatoid arthritis patient. Arthritis Rheum 1983 26(6) 705-11. [Pg.1529]

Honkanen E, Tornroth T, Pettersson E, Skrifvars B. Membranous glomerulonephritis in rheumatoid arthritis not related to gold or D-penicillamine therapy a report of four cases and review of the literature. Clin Nephrol 1987 27(2) 87-93. [Pg.2752]

Shah P, Griffith SM, Shadforth MF, Fisher , Dawes PT, Poulton KV, Thomson W, Ollier WE, Mattey DL Can gold therapy be used more safely In rheumatoid arthritis Adverse drug reactions are more likely In patients with nodular disease, independent of HLA-DR3 status. Rheumatol 2004 31 1903-5. [Pg.148]

Newton et al. [64] studied 27 patients with gold-induced proteinuria, and provided guidelines as to when gold should be permanently stopped in these patients. They demonstrated that proteinuria of up to 2 g/L is compatible with continued gold therapy, since the low risk of more serious nephropathy developing was low. They concluded 1) mild proteinuria (less than 0.4 g/L) is common in rheumatoid arthritis patients on gold, and such a level may not even be re-... [Pg.463]

Kean WF, Lock CJL, Floward-Lock FIE, Buchanan WW. Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis. Arthritis Rheum 1982 25 917-922. [Pg.475]

The decline in the number of reports of parenter-ally administered gold-induced nephropathy may indicate that the dose of gold salts used per injection is decreased and intervals between injections are being extended to prevent adverse reactions. Furthermore, introduction of methotrexate therapy for rheumatoid arthritis has contributed to decreased reliance on gold salts. [Pg.312]

Tubbs RR, Valenzuela R, McGorman U, Pohl MA, Barenberg S. Gold nephropathy. New Eng J Med 1977 296 1413-1414. Yarom R, Stein FI, Peter PD, Slavin S, Flail TA. Nephrotoxic effect of parenteral and intraarticular gold. Ultrastructural and electron microprobe examination of clinical and experimental materials. Arthritis Rheum 1975 99 36-43. lesato K, Mori Y, Ueda S, Wakashin Y Wakashin M, Matsui N, Inoue S, Okuda K. Renal tubular dysfunction as a complication of gold therapy in patients with rheumatoid arthritis. Clin Nephrol 1982 17 46-52. [Pg.320]

Clinical use The major uses of penicillamine are in the treatment of copper poisoning and of Wilson s disease. It is sometimes used as adjunctive therapy in gold, arsenic, and lead intoxication and in rheumatoid arthritis. The agent is water-soluble, well absorbed from the gastrointestinal tract, and excreted unchanged. [Pg.512]

Moller H, Bjorkner B, Bruze M (1996) Clinical reactions to systemic provocation with gold sodium thiomalate in patients with contact allergy to gold. Br J Dermatol 135 423-427 Moller H, Svensson A, Bjorkner B, Bruze B, Lindroth Y, Manthorpe R, Theander J (1997) Contact allergy to gold and gold therapy in patients with rheumatoid arthritis. Acta Derm Venereol 77 370-373... [Pg.549]

Caltabiano MM, Koestler TP, Poste G, Greig RG (1986b) Induction of mammalian stress proteins by a triethylphosphine gold compound used in the therapy of rheumatoid arthritis. Biochem Biophys Res Commum 138 1074-1080 Caltabiano MM, Poste G, Greig RG (1988) Induction of the 32-kD human stress protein by auranofin and related triethylphosphine gold analogs. Biochem Pharmacol 37 4089-4093... [Pg.258]

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