Glyoxal benzyl

Dihydro-2(l,3-dimethyluracil-5-yl)-l,3,4-oxadiazole was obtained in 53% yield by the [3+2] cycloaddition of diazomethane to the formyl group of l,3-dimethyl-5-formyluracil <1997T7045>. The reaction of l-acetyl-2-benzyl-hydrazine with methyl glyoxalate in toluene afforded an oxadiazolidine derivative <1996TL4323>. 

Photolytic. A n-hexane solution containing /n-xylene and spread as a thin film (4 mm) on cold water (10 °C) was irradiated by a mercury medium pressure lamp. In 3 h, 18.5% of the p-xylene photooxidized into p-methylbenzaldehyde, p-benzyl alcohol, p-benzoic acid, and p-methylacetophenone (Moza and Feicht, 1989). Glyoxal and methylglyoxal were produced from the photooxidation of p-xylene by OH radicals in air at 25 °C (Tuazon et al., 1986a). The rate constant for the reaction of p-xylene and OH radicals at room temperature was 1.22 x lO " cmVmolecule-sec (Hansen et al., 1975). A rate constant of 7.45 x 10 L/molecule-sec was reported for the reaction of p-xylene with OH radicals in the gas phase (Darnall et al, 1976). Similarly, a room temperature rate constant of 1.41 x 10 " cm /molecule-sec was reported for the vapor-phase reaction of p-xylene with OH radicals (Atkinson, 1985). At 25 °C, a rate constant of 1.29 x lO " cmVmolecule-sec was reported for the same reaction (Ohta and Ohyama, 1985). 

CL-20 is obtained by the condension of glyoxal with benzylamine in an acid catalyzed reaction to yield hexabenzylhexaaxaisowurtzitane (Fig. 1.8). Afterwards the benzyl groups are replaced under reducing conditions (Pd-C catalyst) by easily removable acetyl substituents. Nitration to form CL-20 takes place in the final reaction step. 

Toluene o-Cresol m-Cresol p-Cresol m-Nitrotoluene o-Nitrotoluene p-Nitrotoluene Benzaldehyde 2-Methyl-p-benzoquinone Benzyl alcohol Benzyl nitrate Glyoxal Methyl glyoxal Methylbutenedial Hydroxymethylbutenedial Oxoheptadienal Methylhydroperoxide Formaldehyde Hexadienyl Hydroxyoxoheptadienyl Maleic anhydride... 

The three part so-called cocktail used to treat HIV positive patients typically comprise a proteinase inhibitor, such as those discussed in Chapter 1 a nucleoside-based reverse transcriptase inhibitor, such as those in Chapter 6, and a non-nucleoside inhibitor of reverse transcriptase (NNRTI). Most of the compounds in the first two classes share a good many structural features with other agents in the class. Chemical structures of the various NNRTIs on the other hand have little in common. Capravirine (103), is notable in the fact that it fails to include any of the fused ring systems that provide the nucleus for other compounds in this class. Chlorination of 3-methylbutyraldehyde (94) provides one of the components for building the imidazole ring. For bookkeeping purposes, the condensation of 94 with 0-benzyl glyoxal and ammonia can be... 

The preparation of certain substituted benzils by treatment of aryl benzyl ketones with selenium dioxide is discussed later (method 183). If a methyl ketone is treated under these conditions, the methyl group is oxidized to an aldehyde group/ The reaction is carried out by refluxing a mixture of selenium dioxide and ketone in dioxane or alcohol for several hours. Preparative details are found in the procedures for phenylglyoxal (72%) and glyoxal (74%) the latter is isolated as its bisulfite derivative. 

Preparations of some A-substituted 2-oxo-l, 2-dihydropyrazines have been discussed in Section 11.2 from the reactions of di-, tri-, and tetrapeptides with glyoxal (380-382) and Cheeseman and co-workers (1111) have described the preparation of 1-benzyl-3-hydroxy-2-oxo-l, 2-dihydropyrazine (83) (and similarly its 1-methyl analogue) from ethyl A-(2, 2 -dimethoxyethyl)oxamate and benzyl-amine through A-benzyl-A -(2, 2-dimethoxyethyl)oxamide (84) by the application of a standard procedure (482). 

Isoquinoline synthesis from aromatic aldehydes or benzyl halides and aminoacetal (Pomeranz-Fritsch) or from benzylamines and glyoxal acetal (Schlitter-Muller) (see 1st edition). 

Amyl acid phosphate Saccharin sodium anhydrous Saccharin sodium dihydrate accelerator, ripening sugarcane Glyoxalic acid accelerator, rubber Aniline 2-Benzothiazyl-N,N-diethylthiocarbamyl sulfide 2-Benzothiazyl-N-morpholine disulfide Benzyl chloride 1,3-Bis (2-benzothiazolylmercaptomethyl) urea Butyl 2-benzothiazole sulfenamide n-Butyraldehyde Cadmium... 

Acetamide Alkyl trimethyl ammonium chloride Ammonium caprylate Benomyl Benzimidazole carbamate 1,2-Benzisothiazolin-3-one Benzyltriethyl ammonium chloride Chlorine dioxide p-Chloro-m-cresol Chlorophene Cocodiamine acetate Dialkyl methyl benzyl ammonium chloride DIchlorobenzyl alcohol DImethoxytetrahydrofuran DM DM hydantoin Glyoxal Hexachlorophene Hydrogenated tallowtrlmonlum methosulfate N,N -Methylene bismorphollne 2-Methyl-4,5-trlmethylene-4-lsothlazolln-3-one Quaternlum-18 methosulfate Thiophanate Tributyl phosphine Tributyl (tetradecyl) phosphonlum chloride Trioctyl (octadecyl) phosphonlum Iodide VInylene bisthlocyanate biocide mfg. 

Formaldehyde, glyoxal, glutaraldehyde, polyaldehyde (polyacrolein), aldehyde-amine condensation products, aldehyde-glycol condensation products, bronopol o-Phenyl phenol, o-benzyl-jn-chlorophenol,p-chloro-m-xylenol, o, p, p -trichloro-o -hydroxydiphenyl ether (Triclosan) Nonylphenoxypoly(ethyleneoxy) ethanol-iodine complex, ethoxylated nonyl phenol-iodine complex, polyvinyl pyrrolidone-iodine complex... 

Formation of isoquinolines by the acid-catalyzed cyclization of benzalaminoacetals prepared from aromatic aldehydes and aminoacetal in the Schlittler-Muller modihcation the starting materials are benzyl amines and glyoxal semiacetal ... 

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