Glycolipids binding proteins

Schroder, M., Schnabel, D., Suzuki, K., and Sandhoff, K., 1991, A mutation in the gene of a glycolipid-binding protein (GM2 activator) that causes GM2-gangliosidosis variant AB, FEBS Lett. 290 1-3. 

Sugars, glycoproteins, and glycolipids Complementary nucleic acids and DNA-/RNA-binding proteins Antibodies... 

Glycolipids are membrane lipids in which the hydrophilic head groups are oligosaccharides, which, as in glycoproteins, act as specific sites for recognition by carbohydrate-binding proteins. 

Carbohydrate-binding proteins Glycolipid Microarray Neoglycolipid Oligosaccharide Abbreviations... 

Transferrin has been shown to be an essential growth factor for T. brucei bloodstream forms and deprivation of cells of transferrin led to growth arrest (88). A 42 kDa transferrin-binding protein of T. brucei, apparently unrelated to the transferrin receptor described above for Leishmania, has been purified and characterized and its corresponding gene was associated with the VSG expression site (89). This binding protein was attached to the plasma membrane via a glycolipid anchor and thus lacked a cytoplasmic domain. Thus far, it is unclear how such a protein could function as a receptor and interact with the intracellular clathrin-coated vesicles supposed to be involved in receptor-mediated uptake of transferrin by the trypanosomes (76). 

Nicholson JK, Holmes E, Wilson ID 2005 Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol 3 431—438 Reed MB, Domenech P, Manca C et al 2004 A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response. Nature 431 84—87 Selvaraj P, Narayanan PR, Reetha AM 1999 Association of functional mutant homozygotes of the marmose binding protein gene with susceptibility to pulmonary tuberculosis in India. Tuber Lung Dis 79 221—227... 

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