Glyceryl Behenate

BP Glycerol dibehenate PhEur Glycerol dibehenas USPNF Glyceryl behenate 

Compritol 888 ATO-, 2,3-dihydroxypropyl docosanoate doc-osanoic acid, 2,3-dihydroxypropyl ester E471 glycerol behenate glyceryl monobehenate. 

Note that tribehenin is used as a synonym for glyceryl tribehenate. 

Docosanoic acid, monoester with glycerin [30233-64-8] (glyceryl behenate) 

Docosanoic acid, diester with glycerin [94201-62-4] (glyceryl dibehenate) 

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SLN for the topical application to the skin are made np from lipids such as glyceryl behenate (Compritol 888 ATO), glyceryl monostearate (Imwitor 900), glyceryl pahnitostearate (Precirol ATO 5), triglycerides (trimyristin, tripalmitin, tristearin), or the wax cetyl pahnitate. Nanodispersions contain 5 to 40% lipid the higher-concentrated preparations have a semisolid appearance. These nanodispersions are cosmetically acceptable as they are, whereas the fluid nanodispersions with lower lipid content shonld be incorporated into, for example, a cream that facilitates the application. 

Glyceryl Behenate occurs as a fine powder. It is a mixture of fatty acid glycerides, primarily glyceryl esters of behenic acid, that melts at about 70°. It is soluble in chloroform and practically insoluble in water and in alcohol. 

Standard Solution Prepare a 6% solution of USP Glyceryl Behenate Reference Standard in chloroform. 

Glyceryl Behenate Glyceryl behenate is a mixture of glycerides of fatty acids which is obtained by esterification of glycerin with behenic acid. It may also contain arachidic acid, stearic acid, erucic acid, lignoceric acid, and palmitic acid. It is available as a waxy mass or powder, possesses a faint odor, and is white in color. It is... 

Glyceryl behenate 0.5 1 Hydrophobic, also used as controlled-release agent... 

Shah, N. H., Stiel, D., Weiss, M., Infeld, M. H., and Malick, A. W. (1986), Evaluation of two new tablet lubricants—Sodium stearyl fumarate and glyceryl behenate. Measurement of physical parameters (compaction, ejection and residual forces) in the tableting process and the effect of the dissolution rate, Drug Dev. Ind. Pharm., 12(8-9), 1329-1346. 

Glyceryl behenate is used in cosmetics, foods, and oral pharmaceutical formulations. In cosmetics, it is mainly used as a viscosity-increasing agent in emulsions see Table I. 

Glyceryl behenate occurs as a fine white powder or hard waxy mass with a faint odor. 

Glyceryl behenate should be stored in a tight container, at a temperature less than 35°C. 

Glyceryl behenate is prepared by the esterification of glycerin by behenic acid (G22 fatty acid) without the use of catalysts. In the case of Compritol 888 ATO (Gattefosse), raw materials used are of vegetable origin, and the esterified material is atomized hy spray-cooling. 

The EINECS numbers are 250-097-0 for glyceryl behenate 303-650-6 for glyceryl dibehenate 242-471-7 for glyceryl tribehenate. 

Obaidat AA, Obaidat RM. Controlled release of tramadol hydrochloride from matrices prepared using glyceryl behenate. Eur J Pharm Biopharm 2001 52(2) 231—235. 

Shah NH, Stiel D, Weiss M, et al. Evaluation of two new tablet lubricants - sodium stearyl fumarate and glyceryl behenate. 

E471 Glyceryl Behenate 304 E952 Sodium Cyclamate 678... 

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